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重组人EGFR(HER1)(表皮生长因子受体)(C端带Fc标签)

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  • 特别提示:包括重组人EGFR(HER1)(表皮生长因子受体)(C端带Fc标签)在内,本公司的所有产品仅可用于科研实验,严禁用于临床YL及其他非科研用途!


    产品名称:重组人EGFR(HER1)(表皮生长因子受体)(C端带Fc标签)
    英文名称:Recombinant Human Epidermal Growth Factor Receptor
    产品货号:JN1258
    产品规格:10μg|50μg|500μg|1mg

    本品由我们的哺乳动物细胞表达系统制备而成,目的基因编码的Leu25-Ser645在C端带有Fc标签。

    EGFR/HER1质量控制:>95%(还原性SDS-PAGE)

    EGFR/HER1制剂:冻干品

    EGFR/HER1保存
    冻干蛋白置于-20℃以下可长期保存,室温条件下可稳定保存3周。
    复溶蛋白溶液可在4~7℃保存2~7天,可分装后置于-20℃保存三个月。

    EGFR/HER1复溶
    打开试剂管前请先离心。
    复溶浓度推荐大于100 μg/ml。
    冻干蛋白请溶于ddH2O。
    复溶后,请根据用量分装冻存,避免反复冻融。

    关于EGFR/HER1
    EGFR is a transmembrane glycoprotein that is a member of the protein kinase superfamily. This protein is a receptor for members of the epidermal growth factor family. EGFR is a cell surface protein that binds to epidermal growth factor. Binding of the protein to a ligand induces receptor dimerization and tyrosine autophosphorylation and leads to cell proliferation. Activates at least 4 major downstream signaling cascades including the RAS-RAF-MEK-ERK, PI3 kinase-AKT, PLCgamma-PKC and STATs modules. May also activate the NF-kappa-B signaling cascade. Also directly phosphorylates other proteins like RGS16, activating its GTPase activity and probably coupling the EGF receptor signaling to the G protein-coupled receptor signaling.

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    温馨提示:不可用于临床ZL。
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