产品货号 : jlcR17482 英文名称 : Sialidase 3 中文名称 : 唾液酸酶3抗体 别 名 : Sialidase3; Sialidase-3; Ganglioside sialidase; Membrane sialidase; N-acetyl-alpha-neuraminidase 3; NEU3. 研究领域 : 肿瘤 细胞生物 信号转导 新陈代谢 表观遗传学 抗体来源 : Rabbit 克隆类型 : Polyclonal 交叉反应 : Human, 产品应用 : ELISA=1:500-1000 IHC-P=1:400-800 IHC-F=1:400-800 ICC=1:100-500 IF=1:100-500 （石蜡切片需做抗原修复） not yet tested in other applications. optimal dilutions/concentrations should be determined by the end user. 分 子 量 : 48kDa 细胞定位 : 细胞膜 性 状 : Lyophilized or Liquid 浓 度 : 1mg/ml 免 疫 原 : KLH conjugated synthetic peptide derived from human Sialidase 3:361-428/428 亚 型 : IgG 纯化方法 : affinity purified by Protein A 储 存 液 : 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol. 保存条件 : Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C. PubMed : PubMed 产品介绍 : This gene product belongs to a family of glycohydrolytic enzymes which remove sialic acid residues from glycoproteins and glycolipids. It is localized in the plasma membrane, and its activity is specific for gangliosides. It may play a role in modulating the ganglioside content of the lipid bilayer. [provided by RefSeq, Jul 2008]
Function: Sialidase-3 plays a role in modulating the ganglioside content of the lipid bilayer at the level of membrane-bound sialyl glycoconjugates.
Subcellular Location: Cell Membrane
Tissue Specificity: Highly expressed in skeletal muscle, testis,adrenal gland and thymus, followed by pancreas, liver, heart and thymus. Weakly expressed in kidney, placenta, brain and lung.
Similarity: Belongs to the glycosyl hydrolase 33 family. Contains 3 BNR repeats.
SWISS: Q9UQ49
Gene ID: 10825
Important Note: This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
