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Recombinant Human Vitronectin/VTN

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  • 公司供应的产品仅用于科研
    产品名称:Recombinant Human Vitronectin/VTN

    溶解性    100μg/ml in distilled water
    保存温度    -20℃
    有效期    3个月
    纯度    ≥ 95%
    Known as    Vitronectin; VN; S-Protein; Serum-Spreading Factor; V75; VTN
    Derived from    Human cells
    Purity    Greater than 95% as determined by reducing SDS-PAGE.
    Formulation    Lyophilized from a 0.2 μm filtered solution of 20mM TrisHCl, 150mM NaCl, pH 8.0.
    Shipping    The product is shipped at ambient temperature.
    Storage    Lyophilized protein should be stored at < -20°C, though stable at room temperature for 3 weeks.Reconstituted protein solution can be stored at 4-7°C for 2-7 days.Aliquots of reconstituted samples are stable at < -20°C for 3 months
    Reconstitution    Always centrifuge tubes before opening. Do not mix by vortex or pipetting.
    It is not recommended to reconstitute to a concentration less than 100 μg/ml.
    Dissolve the lyophilized protein in ddH2O.
    Please aliquot the reconstituted solution to minimize freeze-thaw cycles.
    Endotoxin    Less than 0.1 ng/ug (1 IEU/ug) as determined by LAL test.
    Background    Human Vitronectin/VTN is a cell adhesion and spreading factor. It can be found in the blood and the extracellular matrix (ECM). Vitronectin interacts with glycosaminoglycans and proteoglycans. The multimeric Vitronectin can efficiently bind to and incorporate into the ECM; Vitronectin can support cell adhesion through binding to various integrins and other proteoglycans. Vitronectin can be recognized by certain members of the integrin family and serves as a cell-to-substrate adhesion molecular. It can as a inhibitor of the membrane-damaging effect of the terminal cytolytic complement pathway. Vitronectin contains an endogenous cleavage site, plus cleavage sites for elastase, thrombin, and plasmin.
    Recombinant Human Vitronectin is produced by our Mammalian expression system and the target gene encoding Asp20-Leu478 is expressed with a 6His tag at the C-terminus.
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