Hemagglutinin-neuraminidase

【Molecular Wt.】64 kDa

【Description】Hemagglutinin-neuraminidase refers to a single viral protein that has both hemagglutinin and neuraminidase activity. This is in contrast to the proteins found in influenza, where both functions exist but in two separate proteins. However it does show a structural similarity to influenza viral neuraminidase and has a six-bladed beta-propeller structure. Hemagglutinin-neuraminidase allows the virus to stick to a potential host cell, and cut itself loose if necessary. Hemagglutinin-neuraminidase can be found in a variety of paramyxoviruses including mumps virus, human parainfluenza virus 3, and the avian pathogen Newcastle disease virus.

【Species Reactivity】Avian avulavirus 1

【Tested applications】WB;ELISA

【Antibody type】Rabbit polyclonal Antibody

【Immunogen】Synthetic peptide corresponding to Avian avulavirus 1 Hemagglutinin-neuraminidase aa 223-238.

【Positive control】Hemagglutinin-neuraminidase transfected HEK293 cell.

【Conjugate】Non-conjugated

【Alternative names】

【Form】Liquid

【Stroage】Store at +4℃ after thawing. Aliquot store at -20℃. Avoid repeated freeze / thaw cycles.

【Stroage Buffer】1*TBS (pH7.4), 0.5%BSA, 50%Glycerol. Preservative: 0.05% Sodium Azide.

【Isotype】IgG

【Purity】Peptide affinity purified.

【Subcellular location】Virion membrane.

【Background References】1. Zaitsev V et al. Second sialic acid binding site in Newcastle disease virus hemagglutinin-neuraminidase: implications for fusion. J Virol. 2004 Apr;78(7):3733-41.
2. Lawrence MC et al. Structure of the haemagglutinin-neuraminidase from human parainfluenza virus type III. J Mol Biol. 2004 Jan 30;335(5):1343-57.

【DatasheetURL】https://www.huabio.com/upload/ER1803-50.pdf

【Uniprot ID】B5UA17

【Raised in】Rabbit

【Clone No.】