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苏拉明钠盐

产品信息
  • 规格: 25mg 产品价格: ¥547.0
    规格: 50mg 产品价格: ¥985.0
    规格: 100mg 产品价格: ¥1773.0


    英文名称:Suramin Sodium Salt
    中文名称:苏拉明钠盐
    CAS:129-46-4
    分子式:C51H34N6Na6O23S6
    分子量:1429.15
    产品说明:Suramin Sodium is a sodium salt form of suramin, a polysulphonated naphthylurea with potential antineoplastic activity. Suramin blocks the binding of various growth factors, including insulin-like growth factor I (IGF-I), epidermal growth factor (EGF), platelet-derived growth factor (PDGF), and tumor growth factor-beta (TGF-beta), to their receptors, thereby inhibiting endothelial cell proliferation and migration. This agent also inhibits vascular endothelial growth factor (VEGF)- and basic fibroblast growth factor (bFGF)-induced angiogenesis; retroviral reverse transcriptase; uncoupling of G-proteins from receptors; topoisomerases; cellular folate transport; and steroidogenesis.


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