Human IL-12 R beta 1 & IL-12 R beta 2 (IL-12RB1 & IL-12RB2) Heterodimer Protein

内毒素:
n/a

纯度:
n/a

活性:
n/a

产品背景:
The human IL-12 R subunit is a member of the cytokine receptor superfamily and the functional high-affinity IL-12R is composed of at least two beta-type cytokine receptor subunits, each independently exhibiting a low affinity for IL-12. IL-12 R beta 1 (Interleukin-12 receptor subunit beta-1) is also known as IL-12RB1, CD212. Functions as an interleukin receptor which binds interleukin-12 with low affinity and is involved in IL12 transduction. Associated with IL12RB2 it forms a functional, high affinity receptor for IL12. Associates also with IL23R to form the interleukin-23 receptor which functions in IL23 signal transduction probably through activation of the Jak-Stat signaling cascade.

产品描述:
Human IL-12RB1 & IL-12RB2 Heterodimer Protein is produced by co-expression of IL-12RB1 and IL-12RB2, has a calculated MW of 57.1 kDa (IL-12RB1) and 69.1 kDa (IL-12RB2). Subunit IL-12RB1 contains no tag and subunit IL-12RB2 is fused with polyhistidine tag at the C-terminus.
因为难以在供应系统上进行数据同步//所以了解更多产品规格及产品数据//请移步：
http://www.acrobiosystems.cn/P1582-Human_IL_12_R_beta_1_%26_IL_12_R_beta_2_%28IL_12RB1_%26_IL_12RB2%29_Heterodimer_Protein.html