| 品名 | anti- CD14 antibody |
| 货号 | FNab01426 |
| 规格 | 100µg |
| 状态 | liquid |
| 纯化方法 | Immunogen affinity purified |
| 纯度 | ≥95% as determined by SDS-PAGE |
| 宿主 | Rabbit |
| 亚型 | IgG |
| 存储 | PBS with 0.02% sodium azide and 50% glycerol pH 7.3,-20℃ for 24 months(Avoid repeated freeze / thaw cycles.) |
| 背景介绍 | Coreceptor for bacterial lipopolysaccharide(PubMed:1698311, PubMed:23264655). In concert with LBP, binds to monomeric lipopolysaccharide and delivers it to the LY96/TLR4 complex, thereby mediating the innate immune response to bacterial lipopolysaccharide(LPS)(PubMed:20133493, PubMed:23264655). Acts via MyD88, TIRAP and TRAF6, leading to NF-kappa-B activation, cytokine secretion and the inflammatory response(PubMed:8612135). Acts as a coreceptor for TLR2:TLR6 heterodimer in response to diacylated lipopeptides and for TLR2:TLR1 heterodimer in response to triacylated lipopeptides, these clusters trigger signaling from the cell surface and subsequently are targeted to the Golgi in a lipid-raft dependent pathway(PubMed:16880211). |
| 免疫原 | CD14 molecule |
| 别称 | CD14, CD14 molecule |
| 分子量 | 50-55 kDa |
| Uniprot ID | P08571 |
| 适用种属 | Human, Mouse, Rat |
| 验证应用 | ELISA, IHC, WB, IF, FC |
| 建议稀释比例 | WB: 1:500-1:1000; IHC: 1:100-1:400; IF: 1:50-1:500 |
| 图片 |  | Immunohistochemistry of paraffin-embedded human liver tissue slide using FNab01426(CD14 Antibody) at dilution of 1:200 |
 | HL-60 cells were subjected to SDS PAGE followed by western blot with FNab01426(CD14 Antibody) at dilution of 1:600 |
| 注意事项 | CD14 antibody|CD14抗体仅供科研使用 |
| 产品链接 | https://www.fn-test.cn/product/FNab01426/ |