品名 | anti- CEP63 antibody |
货号 | FNab01606 |
规格 | 100µg |
状态 | liquid |
纯化方法 | Immunogen affinity purified |
纯度 | ≥95% as determined by SDS-PAGE |
宿主 | Rabbit |
亚型 | IgG |
存储 | PBS with 0.02% sodium azide and 50% glycerol pH 7.3,-20℃ for 24 months(Avoid repeated freeze / thaw cycles.) |
背景介绍 | Required for normal spindle assembly. Plays a key role in mother-centriole-dependent centriole duplication; the function seems also to involve CEP152, CDK5RAP2 and WDR62 through a stepwise assembled complex at the centrosome that recruits CDK2 required for centriole duplication. Reported to be required for centrosomal recruitment of CEP152; however, this function has been questioned(PubMed:21983783, PubMed:26297806). Also recruits CDK1 to centrosomes(PubMed:21406398). Plays a role in DNA damage response. Following DNA damage, such as double-strand breaks(DSBs), is removed from centrosomes; this leads to the inactivation of spindle assembly and delay in mitotic progression(PubMed:21406398). |
免疫原 | centrosomal protein 63kDa |
别称 |
分子量 | 57-75kd |
Uniprot ID | Q96MT8 |
适用种属 | Human, Mouse, Rat |
验证应用 | ELISA, WB, IF, IP, IHC |
建议稀释比例 |
图片 |  | Immunohistochemistry of paraffin-embedded human tonsillitis tissue slide using FNab01606(CEP63 Antibody) at dilution of 1:50 |
 | human placenta tissue were subjected to SDS PAGE followed by western blot with FNab01606(CEP63 antibody) at dilution of 1:800 |
注意事项 | CEP63 antibody|CEP63抗体仅供科研使用 |
产品链接 | https://www.fn-test.cn/product/FNab01606/ |