| 品名 | anti- TRIM25 antibody |
| 货号 | FNab08976 |
| 规格 | 100µg |
| 状态 | liquid |
| 纯化方法 | Immunogen affinity purified |
| 纯度 | ≥95% as determined by SDS-PAGE |
| 宿主 | Rabbit |
| 亚型 | IgG |
| 存储 | PBS with 0.02% sodium azide and 50% glycerol pH 7.3,-20℃ for 24 months(Avoid repeated freeze / thaw cycles.) |
| 背景介绍 | Functions as a ubiquitin E3 ligase and as an ISG15 E3 ligase. Involved in innate immune defense against viruses by mediating ubiquitination of DDX58. Mediates 'Lys-63'-linked polyubiquitination of the DDX58 N-terminal CARD-like region which is crucial for triggering the cytosolic signal transduction that leads to the production of interferons in response to viral infection. Promotes ISGylation of 14-3-3 sigma(SFN), an adapter protein implicated in the regulation of a large spectrum signaling pathway. Mediates estrogen action in various target organs. Mediates the ubiquitination and subsequent proteasomal degradation of ZFHX3(PubMed:22452784). |
| 免疫原 | tripartite motif-containing 25 |
| 别称 | EFP,RING finger protein 147, RNF147, TRIM25, tripartite motif containing 25, Z147, Zinc finger protein 147, ZNF147 |
| 分子量 | 116 kDa |
| Uniprot ID | Q14258 |
| 适用种属 | Human, Mouse |
| 验证应用 | ELISA, WB, IF, IP |
| 建议稀释比例 | WB: 1:200-1:2000; IP: 1:200-1:2000; IF: 1:20-1:200 |
| 图片 |  |
 | MCF7 cells were subjected to SDS PAGE followed by western blot with FNab08976(TRIM25 antibody) at dilution of 1:500 |
| 注意事项 | TRIM25 antibody|TRIM25抗体仅供科研使用 |
| 产品链接 | https://www.fn-test.cn/product/FNab08976/ |