品名 | anti- TRADD antibody |
货号 | FNab08915 |
规格 | 100µg |
状态 | liquid |
纯化方法 | Immunogen affinity purified |
纯度 | ≥95% as determined by SDS-PAGE |
宿主 | Rabbit |
亚型 | IgG |
存储 | PBS with 0.02% sodium azide and 50% glycerol pH 7.3,-20℃ for 24 months(Avoid repeated freeze / thaw cycles.) |
背景介绍 | The nuclear form acts as a tumor suppressor by preventing ubiquitination and degradation of isoform p19ARF/ARF of CDKN2A by TRIP12: acts by interacting with TRIP12, leading to disrupt interaction between TRIP12 and isoform p19ARF/ARF of CDKN2A(By similarity). Adapter molecule for TNFRSF1A/TNFR1 that specifically associates with the cytoplasmic domain of activated TNFRSF1A/TNFR1 mediating its interaction with FADD. Overexpression of TRADD leads to two major TNF-induced responses, apoptosis and activation of NF-kappa-B. |
免疫原 | TNFRSF1A-associated via death domain |
别称 | Hs.89862, TRADD |
分子量 | 34 kDa |
Uniprot ID | Q15628 |
适用种属 | Human, Rat |
验证应用 | ELISA, WB, IHC |
建议稀释比例 | WB: 1:200 - 1:2000; IHC: 1:50 - 1:500 |
图片 |  | Immunohistochemistry of paraffin-embedded rat liver tissue slide using FNab08915( TRADD antibody at dilution of 1:200 |
 | Jurkat cells were subjected to SDS PAGE followed by western blot with FNab08915( TRADD Antibody) at dilution of 1:1000 |
注意事项 | TRADD antibody|TRADD抗体仅供科研使用 |
产品链接 | https://www.fn-test.cn/product/FNab08915/ |