Citrullinated Fibrinogen抗体 - Citrullinated Fibrinogen antibody

Citrullinated Fibrinogen monoclonal antibody, clone 3D1，
产品描述：Mouse monoclonal antibody raised against synthetic peptide of Citrullinated Fibrinogen.，
货号：MAB5303，
交叉反应：Mouse，
反应类型：ELISA，
产品类型：Antibody，
抗体来源：Mouse，
特异性：Fibrinogen is a protein produced by the liver which helps stop bleeding by helping blood clots to form. Fibrinogen gets deiminated (conversion from arginin to citrullin) by Peptidyl Arginine Deiminase (PAD) in inflamed joints in patients that develop rheumatoid arthritis. Citrulline, while being an amino acid, is not built into proteins during protein synthesis, as it is not coded for by DNA, yet several proteins are known to contain citrulline. Proteins that normally contain citrulline residues include myelin basic protein (MBP), filaggrin, and several histone proteins, while other proteins, like fibrin and vimentin can get deiminated during cell death and tissue inflammation. Patients with rheumatoid arthritis often (at least 80% of them) develop an immune response against proteins containing citrulline.，
克隆号：3D1，
亚型：IgG1，
免疫原：A synthetic peptide corresponding to mouse Citrullinated Fibrinogen.，
性状：Lyophilized，
储存液：Lyophilized from 10 mM ammonium bicarbonate buffer，
保存条件：Store at 4°C on dry atmosphere. After reconstitution with deionized water, store at -20°C or lower. Aliquot to avoid repeated freezing and thawing.，
规格：100 ug，