免疫原: Activated human peripheral blood mononuclear cells.
规格: 100 ug
HLA-DRB monoclonal antibody, clone SPM289, 产品描述:Mouse monoclonal antibody raised against native human HLA-DRB., 货号:MAB13079, 交叉反应:Human, 反应类型:WB,IHC-P,IF,Flow Cyt, 产品类型:Antibody, 抗体来源:Mouse, 特异性:This monoclonal antibody reacts with the beta-chain of HLA-DR antigen, a member of MHC class II molecules. It does not cross react with HLA-DP and HLA-DQ. The L243 antibody recognizes a different epitope than the HLA-DRB monoclonal antibody, clone SPM289, and these antibodies do not cross-block binding to each other's respective epitopes. HLA-DR is a heterodimeric cell surface glycoprotein comprised of a 36 kDa alpha (heavy) chain and a 28 kDa beta (light) chain. It is expressed on B cells, activated T cells, monocytes/macrophages, dendritic cells and other non-professional APCs. In conjunction with the CD3/TCR complex and CD4 molecules, HLA-DR is critical for efficient peptide presentation to CD4+ T cells. It is an excellent histiocytic marker in paraffin sections producing intense staining. True histiocytic neoplasms are similarly positive. HLA-DR antigens also occur on a variety of epithelial cells and their corresponding neoplastic counterparts., 克隆号:SPM289, 亚型:IgG2b, kappa, 免疫原:Activated human peripheral blood mononuclear cells., 性状:Liquid, 储存液:In 10 mM PBS (0.05% BSA, 0.05% sodium azide)., 保存条件:Store at 4°C., 规格:100 ug,