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Anti-Mouse CD183/CXCR3 Monoclonal Antibody(Biotin Conjugated)[CXCR3-173]

产品信息
  • 产品货号:E-AB-F1114B
    产品类别:流式抗体-抗小鼠 Anti-Mouse)流式抗体
    产品名称:抗小鼠 CD183 流式抗体(Biotin 标记)
              Anti-Mouse CD183 Monoclonal Antibody(Biotin Conjugated)
    Antigen Information
    Alternate Names C-X-C chemokine receptor type 3,Cxcr3,CXC-R3,CXCR-3,Interferon-inducible protein 10 receptor,IP-10 receptor,CD183
    Uniprot ID O88410
    Background CD183, also known as CXCR3, is a member of the C-X-C chemokine family, characterized by a pair of cysteine residues separated by a single amino acid. CXCR3 is a 38 kD seven pass transmembrane receptor coupled to G-protein. It mediates Ca2+ mobilization and chemotaxis in response to C-X-C chemokines, such as IP10 (CXCL10), MIG (CXCL9), I-TAC (CXCL11) and PF4 (CXCL4). CXCR3 is expressed primarily on activiated T lymphocytes, NK cells, and some epithelial cells and endothelial cells. It is not expressed on B cells, monocytes or granulocytes.

    Product Details
    Form Liquid
    Clone No. CXCR3-173
    Host Hamster
    Isotype Hamster IgG
    Reactivity Mouse
    Application FCM
    Storage Buffer PBS with 0.05% Proclin300, 1% BSA
    Shipping Biological ice pack at 4
    Stability & Storage Keep as concentrated solution.
    Store at 2~8 and protected from prolonged exposure to light. Do not freeze.

    Centrifuge before opening to ensure complete recovery of vial contents.
    This product is guaranteed up to one year from purchase.

    Recommended Use
    Each lot of this antibody is quality control tested by immunofluorescent staining with flow cytometric analysis. For flow cytometric staining, the suggested use of this reagent is 2.0 µg per 10<sup>6</sup> cells in 100 µl volume or 100 µl of whole blood. It is recommended that the reagent be titrated for optimal performance for each application.

    Related Protocols
    流式细胞表面染色步骤
    流式细胞术样本制备技术

    Troubleshooting
    流式实验常见问题及解决方案

    References
    1. Krug A, Uppaluri R, Facchetti F, et al. J Immunol. 2002; 169(11):6079-6083.
    2. Soto H, Wang W, Strieter RM, et al. Proc Natl Acad Sci U S A. 1998; 95(14):8205-8210.
    3. Tamaru M, Tominaga Y, Yatsunami K, Narumi S. Biochem Biophys Res Commun. 1998; 251(1

    点击查看流式抗体(flow cytometry antibody)列表
    更多详情请参见Elabscience官方网站
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