产品英文名称: Recombinant Human Angiostatin Kringles 1-3
英文简称:Angiostatin K1-3
中文名称:重组人血管生成YZ因子Kringles 1-3
背景资料:Ang K1-3 is a proteolytic fragment of plasminogen containing the first thrAngiostatin Human Recombinant produced in E.coli is a single, non-glycosylated polypeptide chain containing 259 amino acids and having a molecular mass of approximately 30.0 kDa.The Ang K1-3 is purified by proprietary chromatographic techniques. kringle structures. A specific inhibitor of endothelial cell growth and angiogenesis. More active relative to kringles 1-4. Ang K1-3 reduces endothelial cell proliferation and acts as a potent inhibitor of angiogenesis and tumor growth.
产品描述:Angiostatin Human Recombinant produced in E.coli is a single, non-glycosylated polypeptide chain containing 259 amino acids and having a molecular mass of approximately 30.0 kDa.The Ang K1-3 is purified by proprietary chromatographic techniques.
来源宿主:大肠杆菌中重组表达
序列:VYLSECKTGN GKNYRGTMSK TKNGITCQKW SSTSPHRPRF SPATHPSEGL EENYCRNPDN DPQGPWCYTT DPEKRYDYCD ILECEEECMH CSGENYDGKI SKTMSGLECQ AWDSQSPHAH GYIPSKFPNK NLKKNYCRNP DRELRPWCFT TDPNKRWELC DIPRCTTPPP SSGPTYQCLKGTGENYRGNV AVTVSGHTCQ HWSAQTPHTH NRTPENFPCK NLDENYCRNP DGKRAPWCHT TNSQVRWEYC KIPSCDSSP.
溶解建议:Sterile Filtered White lyophilized (freeze-dried) powder. Lyophilized from a 0.2um filtered concentrated (1.0mg/ml) solution in 20mM NaAc, pH5.5, 4% mannitol. We recommend to briefly centrifuge the vial prior to opening to bring the contents to the bottom. Reconstitute in sterile distilled water or aqueous buffer containing 0.1% BSA to a concentration of 0.1-1.0 mg/ml. Stock solutions should be apportioned into working aliquots and stored at <-20°C. Further dilutions should be made in appropriate buffered solutions.
保存建议:The lyophilized Angiostatin K1-3 is stable for several weeks at 2-8℃, but should be kept at -20℃ for long term storage, preferably desiccated. Upon reconstitution, the preparation is stable for up to one week at 2-8℃. For maximal stability, apportion the reconstituted preparation into working aliquots and store at -20℃ to -70℃.Avoid repeated freeze/thaw cycles.
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温馨提示:不可用于临床ZL。