产品英文名称: Recombinant Human Gelatin
英文简称:Gelatin
中文名称:重组人明胶
背景资料:Gelatin is a translucent, colorless, brittle, virtually tasteless solid substance. Historically, gelatin is denatured collagen and is typically isolated from bovine or porcine skin or bone by acid or base extraction. Approximately fifty thousand metric tons of gelatins are produced annually for medical use. Most of this volume is consumed in some aspect of oral drug delivery, which uses mixtures of bovine and porcine gelatin. Additionally, thousands of metric tons are used annually for parenteral formulations and devices.Gelatin melts when heated and solidifies when cooled again. Together with water, gelatin forms a semi-solid colloid gel. Gelatin forms a solution of high viscosity in water, which sets to a gel on cooling.Currently available gelatin preparations consist of a distribution of polypeptide fragments of di毕赤酵母中重组表达erent sizes, di毕赤酵母中重组表达erent isoelectric points (pI), and di毕赤酵母中重组表达erent gelling properties, and often exhibit lot-to-lot variability. Furthermore the physiochemical properties of these gelatins vary depending on method of extraction, amount of thermal denaturation employed, and electrolyte content of the resulting material.The variable nature of such gelatin preparations, therefore, presents a significant challenge to those who use these protein mixtures in the manufacture of other products. Gelatin hydrolysates represent a specialized preparation for use in situations where gel formation is not desired, such as in the stabilization of vaccines and biologics or in other liquid formulations. Extracted from animal sources, this type of gelatin requires additional processing steps such as thermal hydrolysis or treatment with a protease.Using recombinant technology, gelatins are highly purified, fully characterized, genetically distinct molecules that can replace hydrolyzed animal gelatin and other excipients currently used in a variety of applications.Recombinant gelatins eliminate many of the variables and drawbacks associated with tissue-derived material. This technology allows the production of gelatins with defined molecular weights, pI, guarantRecombinant Gelatin having a molecular mass of 8,500 dalton using a recombinant yeast system (Pichia pastoris) to express specified fragments of Type I, alpha1 human sequence collagen.d lot-to-lot reproducibility, and the ability to tailor the molecule to match a specific application.
产品描述:Recombinant Gelatin having a molecular mass of 8,500 dalton using a recombinant yeast system (Pichia pastoris) to express specified fragments of Type I, alpha1 human sequence collagen.
来源宿主:毕赤酵母中重组表达
序列:溶解建议:Sterile Filtered white lyophilized powder. The protein was lyophilized from a concentrated solution containing no additives.
保存建议:Gelatin can be stored at room temperature, for long term storage at-20℃.
其他简介: ProSpec是一家细胞因子蛋白及相关抗体生产和研发品Pai。ProSpec的生产和研发工厂位于以色列,专注于蛋白(重组及合成)生产研发,其独有的细菌和哺乳动物表达和蛋白折叠技术使其能在17年内成长为国际的科研级蛋白供应商。目前ProSpec可以提供细胞因子,生长因子,激素,信号蛋白,病毒抗原等近800种重组蛋白和100多种抗体,是世界上提供蛋白品种Z多的公司之一,领先的生产工艺和规模使其可以提供毫克到克级蛋白,价格优于同类公司。绝大部分产品是天然成熟型蛋白,而不含有标签蛋白。考虑到大部分研究者希望能更灵活地配制蛋白溶液,ProSpec-Tany绝大部分产品没有添加保护剂或盐,这就对工艺提出了更高的要求。同时,ProSpec-Tany绝大部分产品为冻干粉,因此易于运输和保存。
温馨提示:不可用于临床ZL。