品Pai:miltenyi，产品名称：CD334 (FGFR4)-PE, human
CD334 (FGFR4) antibodies, human - Miltenyi Biotec
货号：130-110-009
Clone 4FR6D3 recognizes the human CD334 antigen, known as fibroblast growth factor receptor 4 (FGFR4) which is a member of the fibroblast growth factor receptor family. This cell surface tyrosine kinase is a high affinity receptor for both acidic and basic fibroblast growth factor. The binding of CD334 with the acidic fibroblast growth factors FGF2, FGF6, and FGF8, FGF19, and GFG1 induces mitogenesis and differentiation. CD334 is expressed in adrenal, lung, kidney, liver, pancreas, intestine, striated muscle, and spleen tissues of human fetuses. A soluble-form splice variant of FGFR 4 was identified in human gastrointestinal epithelial cells and cancer cells.
| Clone | Isotype |
|---|---|
| 4FR6D3 | mouse IgG1κ |
