CD183 (CXCR3)-VioBright FITC/CD183 (CXCR3) antibodies, human

品Pai:miltenyi，产品名称：CD183 (CXCR3)-VioBright FITC, human
CD183 (CXCR3) antibodies, human - Miltenyi Biotec
货号：130-106-009
Clone REA232 recognizes CD183, a 38 kDa G protein–coupled chemokine receptor. CD183 harbors seven-transmembrane α-helices, an extracellular N-terminal domain containing three loops involved in the chemokine ligand binding, an intracellular C-terminal domain involved in signal transduction. CD183 binds CXCL9, CXCL10, and CXCL11 as ligands. CD183-ligand interactions play role in diverse cellular functions such as chemotactic migration, cell proliferation, and death. Expression of CD183 is found on T cells, human airway epithelial cells, NK cells, plasmacytoid dendritic cells, mast cells, alveolar macrophages, and eosinophils.
Additional information: Clone REA232 displays negligible binding to Fc receptors.

Alternative namesCXCR3, CD183, CKR-L2, CMKAR3, GPR9, IP10-R, Mig-R, MigR

Clone and isotype

Clone	Isotype
REA232	recombinant human IgG1