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Notch2-Biotin/Anti-Notch2 antibodies, mouse

产品信息



  • 品Pai:miltenyi，产品名称：Anti-Notch2-Biotin, mouse 200 tests
    Anti-Notch2 antibodies, mouse - Miltenyi Biotec
    货号：130-101-880
    Clone HMN2-35 recognizes Notch2, a member of the Notch receptor family. Notch2 acts as a receptor for the membrane bound ligands Jagged1, Jagged2 and Delta1. Notch signaling pathway is evolutionary conserved in the animal kingdom, where Notch receptors upon ligand binding undergo two proteolytic cleavages. The second cleavage releases the Notch intracellular domain (NICD), which translocates into the nucleus, forms an activator complex with the DNA binding protein RBP-J and activates genes of the enhancer of split locus. Notch signaling network regulates a number of biological processes involved in determination of cell fate, cell differentiation and apoptosis etc.

    Alternative namesN2
    Clone and isotype
    Clone Isotype
    HMN2-35 hamster IgG

     

    温馨提示：不可用于临床ZL。
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