CD206-APC-Vio770/CD206 antibodies, human

品Pai:miltenyi，产品名称：CD206-APC-Vio770, human
CD206 antibodies, human - Miltenyi Biotec
货号：130-100-226
The mannose receptor (MR), also known as macrophage MR or CD206, is a 162–175 kDa type I membrane protein. It contains an N-terminal cystein-rich domain and eight C-type lectin-like domains (CTLDs), beside a transmembrane and a cytoplasmic domain. CD206 is expressed by macrophages, dendritic cells, and subsets of endothelial cells, but not on monocytes. The MR recognizes multiple mainly microbial carbohydrates with mannose, fucose, or N-acetyl glucosamine residues. The MR mediates endocytosis and phagocytosis, linked to antigen presentation. It plays an important role in host defense and provides a link between innate and adaptive immunity.

Alternative namesMRC1, CLEC13D, CLEC13DL, MMR, MRC1L1

Clone and isotype

Clone	Isotype
DCN228	mouse IgG1κ