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Notch2-PE/Anti-Notch2 antibodies, human

产品信息


  • 品Pai:miltenyi,产品名称:Anti-Notch2-PE, human
    Anti-Notch2 antibodies, human - Miltenyi Biotec
    货号:130-096-977
    Upon binding its membrane-bound ligand of the Delta-like or Jagged family members, the Notch receptor undergoes two proteolytic cleavage steps eventually releasing the Notch intracellular domain (NICD), which subsequently translocates into the nucleus, where it activates transcription within a multiprotein complex. Notch2 is expressed on various hematopetic cells, including T cell precursors in the thymus and activated peripheral T cells. In addition, the altered expression of Notch2 in various leukemias, lymphomas and cancers has been reported.

    Alternative namesAGS2, HJCYS, hN2
    Clone and isotype
    CloneIsotype
    MHN2-25mouse IgG2aκ

    温馨提示:不可用于临床ZL。
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