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CD158e (KIR3DL1)-APC/CD158e (KIR3DL1) antibodies, human

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  • 品Pai:miltenyi,产品名称:CD158e (KIR3DL1)-APC, human
    CD158e (KIR3DL1) antibodies, human - Miltenyi Biotec
    货号:130-092-474
    Clone DX9 recognizes CD158e (KIR3DL1), a member of the killer immunoglobulin-like receptor (KIR) family expressed on CD56dimCD16+ natural killer (NK) cells and CD8+ T cells. KIRs contribute to the regulation of NK cell-mediated cytotoxicity. They are monomeric receptors possessing high allelic polymorphism with either 2 or 3 Ig-like extracellular domains. According to the length of their cytoplasmic tail, KIRs can be further subdivided into inhibitory KIRs and activating KIRs (KIR2DS or KIR3DS). KIR3DL1 provides an inhibitory signal of NK cell lytic activity upon interaction with its specific ligand, HLA-Bw4.

    Alternative namesKIR3DL1, NKB1, NKB1B, p70
    Clone and isotype
    CloneIsotype
    DX9mouse IgG1κ

    温馨提示:不可用于临床ZL。
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