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FITC标记的神经视锥蛋白样1抗体(神经钙蛋白)

产品信息
  • FITC标记的神经视锥蛋白样1抗体(神经钙蛋白)
    英文名称 Anti-VILIP1/FITC
    中文名称 FITC标记的神经视锥蛋白样1抗体(神经钙蛋白)
    别    名 VILIP-1; 21 kDa CABP; Hippocalcin like protein 3; HLP 3; HLP3; HPCAL 3; HPCAL3; HUVISL1; Neural visinin-like protein 1; Neural visinin-like type 1 protein; Neurocalcin alpha; NVL 1; NVL1; Nvp1; OZ1; Ratnvp1; VILIP; Visinin; Visinin like 1; Visinin like protein 1; VISL 1; VISL1; Vnsl1; VISL1_HUMAN.  
    规格价格 100ul/2980元 购买        大包装/询价
    说 明 书 100ul  
    研究领域 肿瘤  细胞生物  神经生物学  信号转导  结合蛋白  Alzheimer's  
    抗体来源 Rabbit
    克隆类型 Polyclonal
    交叉反应 Human, Mouse, Rat, Chicken, Pig, Cow, 
    产品应用 IF=1:50-200  
    not yet tested in other applications.
    optimal dilutions/concentrations should be determined by the end user.
    分 子 量 22kDa
    性    状 Lyophilized or Liquid
    浓    度 1mg/ml
    免 疫 原 KLH conjugated synthetic peptide derived from human VILIP1
    亚    型 IgG
    纯化方法 affinity purified by Protein A
    储 存 液 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.
    保存条件 Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C.
    产品介绍 background:
    This gene is a member of the visinin/recoverin subfamily of neuronal calcium sensor proteins. The encoded protein is strongly expressed in granule cells of the cerebellum where it associates with membranes in a calcium-dependent manner and modulates intracellular signaling pathways of the central nervous system by directly or indirectly regulating the activity of adenylyl cyclase. Alternatively spliced transcript variants have been observed, but their full-length nature has not been determined.

    Function:
    Regulates (in vitro) the inhibition of rhodopsin phosphorylation in a calcium-dependent manner. 

    Tissue Specificity:
    Brain and retina. Neuron-specific in the central and peripheral nervous system. Increased in the cerebrospinal fluid of Alzheimer disease patients (at protein level).

    Similarity:
    Belongs to the recoverin family. 
    Contains 4 EF-hand domains. 

    Database links:

    Entrez Gene: 396189 Chicken

    Entrez Gene: 282124 Cow

    Entrez Gene: 7447 Human

    Entrez Gene: 26950 Mouse

    Entrez Gene: 100173440 Orangutan

    Entrez Gene: 24877 Rat

    Omim: 600817 Human

    SwissProt: P62764 Chicken

    SwissProt: P62763 Cow

    SwissProt: Q4R5F7 Cynomolgus Monkey

    SwissProt: P62760 Human

    SwissProt: P62761 Mouse

    SwissProt: Q5RD22 Orangutan

    SwissProt: P62762 Rat

    Unigene: 444212 Human

    Unigene: 27005 Mouse

    Unigene: 105934 Rat



    Important Note:
    This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
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