Name:PAR-4 (1-6)) |Protease Activated Receptor-4 (1-6), human;
Sequence(Three Letter):H-Gly-Tyr-Pro-Gly-Gln-Val-OH (trifluoroacetate salt);
Sequence(One Letter):GYPGQV;
Cas:[225779-44-2];
Formula:C28H41N7O9;
M.W.:619.68;
Size:1mg,5mg,10mg,50mg,100mg,1g;
Purity:80%,90%,95%,98%,99%;
Storage Temp:Store at -20°C. Keep tightly closed. Store in a cool dry place.;
Reference:W.-F.Xu et al., Proc. Natl. Acad. Sci. USA, 95, 6642 (1998)H.Andersen et al., Proc. Natl. Acad. Sci. USA, 96, 11189 (1999)R.Kaufmann et al., J. Cancer Res. Clin. Oncol., 126, 91 (2000);
Description:This peptide is the amino terminus of the fourth protease-activated receptor (PAR4) after the cleavage at Arg47/Gly48 was tested for its ability to stimulate COS cells expressing PAR4. The peptide readily activated both wild-type and mutant PAR4 (R47A) at 500 碌M, whereas thrombin and trypsin only activate the wild-type PAR4.
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