Lamin B核纤层蛋白B单克隆抗体(细胞核膜标志物)_详细资料

[免疫学试剂] 一抗抗原抗体 Anti-HNF-1α 肝<em>细胞核</em>因子1α抗体

[免疫学试剂] 一抗抗原抗体 Anti-HNF-1α 肝细胞核因子1α抗体: 型号：[免疫学试剂] 一抗抗原抗体

[酶联免疫试剂盒] 人类ELISA试剂盒人抗增殖<em>细胞核</em>抗原抗体(PCNA)ELISA Kit

[酶联免疫试剂盒] 人类ELISA试剂盒人抗增殖细胞核抗原抗体(PCNA)ELISA Kit: 型号：[酶联免疫试剂盒] 人类ELISA试剂盒

[酶联免疫试剂盒] 人类ELISA试剂盒人抗中性粒<em>细胞核</em>周抗体(pANCA)ELISA Kit

[酶联免疫试剂盒] 人类ELISA试剂盒人抗中性粒细胞核周抗体(pANCA)ELISA Kit: 型号：[酶联免疫试剂盒] 人类ELISA试剂盒

[酶联免疫试剂盒] 大鼠ELISA试剂盒大鼠抗中性粒<em>细胞核</em>周抗体(pANCA)ELISA Kit

[酶联免疫试剂盒] 大鼠ELISA试剂盒大鼠抗中性粒细胞核周抗体(pANCA)ELISA Kit: 型号：[酶联免疫试剂盒] 大鼠ELISA试剂盒

[酶联免疫试剂盒] 大鼠ELISA试剂盒大鼠抗增殖<em>细胞核</em>抗原抗体(PCNA)ELISA Kit

[酶联免疫试剂盒] 大鼠ELISA试剂盒大鼠抗增殖细胞核抗原抗体(PCNA)ELISA Kit: 型号：[酶联免疫试剂盒] 大鼠ELISA试剂盒

[酶联免疫试剂盒] 小鼠ELISA试剂盒小鼠抗中性粒<em>细胞核</em>周抗体(pANCA)ELISA Kit

[酶联免疫试剂盒] 小鼠ELISA试剂盒小鼠抗中性粒细胞核周抗体(pANCA)ELISA Kit: 型号：[酶联免疫试剂盒] 小鼠ELISA试剂盒

[酶联免疫试剂盒] 小鼠ELISA试剂盒小鼠抗增殖<em>细胞核</em>抗原抗体(PCNA)ELISA Kit

[酶联免疫试剂盒] 小鼠ELISA试剂盒小鼠抗增殖细胞核抗原抗体(PCNA)ELISA Kit: 型号：[酶联免疫试剂盒] 小鼠ELISA试剂盒

人髓性细胞核分化抗原（MNDA）ELISA kit

人抗增殖细胞核抗原抗体（PCNA）ELISA kit

人抗中性粒细胞核周抗体（pANCA）ELISA kit

大鼠抗中性粒细胞核周抗体(pANCA)ELISA kit

大鼠抗增殖细胞核抗原抗体(PCNA)ELISA kit

英文名称	Lamin B
中文名称	核纤层蛋白B单克隆抗体(细胞核膜标志物)
别名	lamin B1; LMB1; LMN; LMN2; LMNB 1; LMNB; LMNB1; MGC111419; LMNB1_HUMAN; Lamin-B1.
规格价格	50ul/860元购买 100ul/1580元购买大包装/询价
说明书	50ul 100ul
产品类型	内参抗体
研究领域	细胞生物染色质和核信号信号转导细胞凋亡细胞类型标志物
抗体来源	Mouse
克隆类型	Monoclonal
克隆号	9C11
交叉反应	Human, Mouse, Rat,
产品应用	WB=1:500-1000 ELISA=1:500-1000 （石蜡切片需做抗原修复） not yet tested in other applications. optimal dilutions/concentrations should be determined by the end user.
分子量	64kDa
细胞定位	细胞核
性状	Lyophilized or Liquid
浓度	1mg/ml
免疫原	Recombinant human Lamin B Protein:
亚型	IgG1
纯化方法	affinity purified by Protein G
储存液	0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.
保存条件	Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C.
PubMed	PubMed
产品介绍	background: The nuclear lamina consists of a two-dimensional matrix of proteins located next to the inner nuclear membrane. The lamin family of proteins make up the matrix and are highly conserved in evolution. During mitosis, the lamina matrix is reversibly disassembled as the lamin proteins are phosphorylated. Lamin proteins are thought to be involved in nuclear stability, chromatin structure and gene expression. Vertebrate lamins consist of two types, A and B. This gene encodes one of the two B type proteins, B1. Alternative splicing results in transcript variants and a duplication of this gene is associated with autosomal dominant adult-onset leukodystrophy (ADLD). [provided by RefSeq, Oct 2010]. Function: Lamins are components of the nuclear lamina, a fibrous layer on the nucleoplasmic side of the inner nuclear membrane, which is thought to provide a framework for the nuclear envelope and may also interact with chromatin Subunit: Homodimer. Interacts with lamin-associated polypeptides IA, IB and 2. Subcellular Location: Nucleus inner membrane; Lipid-anchor; Nucleoplasmic side Post-translational modifications: B-type lamins undergo a series of modifications, such as farnesylation and phosphorylation. Increased phosphorylation of the lamins occurs before envelope disintegration and probably plays a role in regulating lamin associations. DISEASE: Defects in LMNB1 are the cause of leukodystrophy demyelinating autosomal dominant adult-onset (ADLD) [MIM:169500]. ADLD is a slowly progressive and fatal demyelinating leukodystrophy, presenting in the fourth or fifth decade of life. Clinically characterized by early autonomic abnormalities, pyramidal and cerebellar dysfunction, and symmetric demyelination of the CNS. It differs from multiple sclerosis and other demyelinating disorders in that neuropathology shows preservation of oligodendroglia in the presence of subtotal demyelination and lack of astrogliosis. Similarity: Belongs to the intermediate filament family. SWISS: P20700 Gene ID: 4001 Database links: Entrez Gene: 396223 Chicken Entrez Gene: 4001 Human Entrez Gene: 16906 Mouse Entrez Gene: 116685 Rat Omim: 150340 Human SwissProt: P14731 Chicken SwissProt: P20700 Human SwissProt: P14733 Mouse SwissProt: P70615 Rat Unigene: 89497 Human Unigene: 4105 Mouse Unigene: 11362 Rat Important Note: This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
产品图片	Sample:MOLT-4 Cell (Human) Lysate at 40 ug Primary: Anti-LaminB(bsm-33040M)at 1/1000 dilution Secondary: IRDye800CW Goat Anti-Mouse IgG at 1/20000 dilution Predicted band size: 64kD Observed band size: 64kD