Cystatin SN胱抑素SN/半胱氨酸蛋白酶YZ剂SN抗体

Cystatin SN胱抑素SN/半胱氨酸蛋白酶YZ剂SN抗体

英文名称	Cystatin SN
中文名称	胱抑素SN/半胱氨酸蛋白酶YZ剂SN抗体
别    名	CST1; Cystain SAI; Cystain-SA-I; Cystatin 1; Cystatin-1; Cystatin-SN; Cystatin1; Cysteine proteinase inhibitor, type 2 family; CYTN; CYTN_HUMAN; Salivary cystatin SA1; Salivary cystatin-SA-1.
规格价格	100ul/1380元 购买    200ul/2200元 购买    大包装/询价
说 明 书	100ul  200ul
研究领域	细胞生物  信号转导  泛素
抗体来源	Rabbit
克隆类型	Polyclonal
交叉反应	Human,
产品应用	ELISA=1:500-1000 IHC-P=1:400-800 IHC-F=1:400-800 ICC=1:100-500 IF=1:100-500 （石蜡切片需做抗原修复）  not yet tested in other applications. optimal dilutions/concentrations should be determined by the end user.
分 子 量	14kDa
细胞定位	细胞浆
性    状	Lyophilized or Liquid
浓    度	1mg/ml
免 疫 原	KLH conjugated synthetic peptide derived from human Cystatin SN:81-141/141
亚    型	IgG
纯化方法	affinity purified by Protein A
储 存 液	0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.
保存条件	Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C.
PubMed	PubMed
产品介绍	background: The cystatin superfamily encompasses proteins that contain multiple cystatin-like sequences. Some of the members are active cysteine protease inhibitors, while others have lost or perhaps never acquired this inhibitory activity. There are three inhibitory families in the superfamily, including the type 1 cystatins (stefins), type 2 cystatins and the kininogens. The type 2 cystatin proteins are a class of cysteine proteinase inhibitors found in a variety of human fluids and secretions, where they appear to provide protective functions. The cystatin locus on chromosome 20 contains the majority of the type 2 cystatin genes and pseudogenes. This gene is located in the cystatin locus and encodes a cysteine proteinase inhibitor found in saliva, tears, urine, and seminal fluid. [provided by RefSeq, Jul 2008] Function: Human saliva appears to contain several cysteine proteinase inhibitors that are immunologically related to cystatin S but that differ in their specificity due to amino acid sequence differences. Cystatin SN, with a pI of 7.5, is a much better inhibitor of papain and dipeptidyl peptidase I than is cystatin S, although both inhibit ficin equally well. Subcellular Location: Secreted. Tissue Specificity: Expressed in submandibular and sublingual saliva but not in parotid saliva (at protein level). Expressed in saliva, tears, urine and seminal fluid. Similarity: Belongs to the cystatin family. SWISS: P01037 Gene ID: 1469 Database links: Entrez Gene: 1469 Human Omim: 123855 Human SwissProt: P01037 Human Unigene: 123114 Human Important Note: This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.