特别声明：本产品及我公司所售其他产品均为科研类试剂产品，严禁用于药物、YL及其他非科研用途。
北京百奥莱博专业生产销*(代"售")重组人分子伴侣辅因子(热休克蛋白70羧基末端相互作用蛋白)(CHIP)(STUB1)价格，我公司供应的分子生物学试剂品类齐全，且具有优势价格，欢迎新老客户垂询订购。
名称：重组人分子伴侣辅因子(热休克蛋白70羧基末端相互作用蛋白)(CHIP)(STUB1)价格
编号：JN1919
规格：10μg|50μg|500μg|1mg
英文名：Recombinant Human E3 Ubiquitin-Protein Ligase CHIP
品Pai：百奥莱博
产地：北京
本品由我们的大肠杆菌表达系统制备而成，目的基因编码的Met1-Tyr303表达纯化得来。
STUB1/CHIP质量控制：＞95%(还原性SDS-PAGE)
STUB1/CHIP制剂：液体
STUB1/CHIP保存：收到货后请置于-20℃，可保存6个月，避免反复冻融。
关于STUB1/CHIP：
E3 Ubiquitin-Protein Ligase CHIP is a cytoplasmic protein. CHIP is highly expressed in skeletal muscle, heart, pancreas, brain and placenta. CHIP interacts with the molecular chaperones Hsc70-Hsp70 and Hsp90 through its TPR domain; lead to in client substrate ubiquitylation and degradation by the proteasome. CHIP targets misfolded chaperone substrates towards proteasomal degradation. CHIP mediates transfer of non-canonical short ubiquitin chains to HSPA8 that have no effect on HSPA8 degradation. CHIP plays a role in base-excision repair: catalyzes polyubiquitination by amplifying the HUWE1/ARF-BP1-dependent monoubiquitination and leading to POLB-degradation by the proteasome. It also may regulate the receptor stability and activity through proteasomal degradation..jpg)
欲咨询购买重组人分子伴侣辅因子(热休克蛋白70羧基末端相互作用蛋白)(CHIP)(STUB1)价格，请致电北京百奥莱博科技有限公司，为您提供Z全面周到的产品服务，除此之外，我公司正在促销以下产品：
·重组人BTLA
编号：JN1868
英文名称：Recombinant Human B- and T-Lymphocyte Attenuator
规格：10μg|50μg|500μg|1mg
本品由我们的哺乳动物细胞表达系统制备而成，目的基因编码的Lys31-Leu150在C端带有Fc标签。
BTLA质量控制：＞95%(还原性SDS-PAGE)
BTLA制剂：冻干品
BTLA保存：
冻干蛋白置于-20℃以下可长期保存，室温条件下可稳定保存3周。
复溶蛋白溶液可在4～7℃保存2～7天，可分装后置于-20℃保存三个月。
BTLA复溶：
打开试剂管前请先离心。
复溶浓度推荐大于100μg/ml。
冻干蛋白请溶于ddH2O。
复溶后，请根据用量分装冻存，避免反复冻融。
关于BTLA：
B- and T-Lymphocyte Attenuator (BTLA) is a single-pass type I membrane protein containing 1 Ig-like V-type (immunoglobulin-like) domain. BTLA expression is induced during activation of T cells, and BTLA remains expressed on Th1 cells but not Th2 cells. Like PD1 and CTLA4, BTLA interacts with a B7 homolog, B7H4. However, unlike PD-1 and CTLA-4, BTLA displays T-Cell inhibition via interaction with tumor necrosis family receptors (TNF-R), not just the B7 family of cell surface receptors. BTLA is a lymphocyte inhibitory receptor that inhibits lymphocytes during immune response. BTLA also is a ligand for tumor necrosis factor (receptor) superfamily, member 14 (TNFRSF14), also known as herpes virus entry mediator (HVEM). BTLA-HVEM complexes negatively regulate T-cell immune responses.
重组人分子伴侣辅因子(热休克蛋白70羧基末端相互作用蛋白)(CHIP)(STUB1)价格关键词：重组人STUB1,重组人分子伴侣辅因子,JN1919,重组人CHIP,重组人热休克蛋白70羧基末端相互作用蛋白.jpg)
·重组人SUMO3(小泛素相关修饰物3)
编号：JN1174
英文名称：Recombinant Human Small Ubiquitin-Related Modifier 3
规格：10μg|50μg|500μg|1mg
本品由我们的大肠杆菌表达系统制备而成，目的基因编码的Met1-Phe103表达纯化得来。
SUMO3质量控制：＞95%(还原性SDS-PAGE)
SUMO3制剂：冻干品
SUMO3保存：
冻干蛋白置于-20℃以下可长期保存，室温条件下可稳定保存3周。
复溶蛋白溶液可在4～7℃保存2～7天，可分装后置于-20℃保存三个月。
SUMO3复溶：
打开试剂管前请先离心。
复溶浓度推荐大于100μg/ml。
冻干蛋白请溶于ddH2O。
复溶后，请根据用量分装冻存，避免反复冻融。
关于SUMO3：
SUMO3 belongs to the SUMO protein family and operates like ubiquitin. Ubiquitin-like protein which can be covalently attached to target lysines either as a monomer or as a lysine-linked polyer. Nevertheless unlike ubiquitin that targets proteins for degration, SUMO3 takes part in several cellular processess, such as nuclear transport, transcription regulation, apoptosis and protein stability. SUMO3 participates in amyloid beta generation and has a key role in the oneset or progression of Alzheimers disease.
重组人分子伴侣辅因子(热休克蛋白70羧基末端相互作用蛋白)(CHIP)(STUB1)价格关键词：重组人STUB1,重组人分子伴侣辅因子,JN1919,重组人CHIP,重组人热休克蛋白70羧基末端相互作用蛋白.jpg)
·重组小鼠IL-23R
编号：JN1442
英文名称：Recombinant Mouse Interleukin-23 Receptor
规格：10μg|50μg|500μg|1mg
本品由我们的哺乳动物细胞表达系统制备而成，目的基因编码的Gly24-Asp372在C端带有Fc标签。
IL-23R质量控制：＞95%(还原性SDS-PAGE)
IL-23R制剂：冻干品
IL-23R保存：
冻干蛋白置于-20℃以下可长期保存，室温条件下可稳定保存3周。
复溶蛋白溶液可在4～7℃保存2～7天，可分装后置于-20℃保存三个月。
IL-23R复溶：
打开试剂管前请先离心。
复溶浓度推荐大于100μg/ml。
冻干蛋白请溶于ddH2O。
复溶后，请根据用量分装冻存，避免反复冻融。
关于IL-23R：
Interleukin 23 receptor (IL23R), a heterodimer of the IL12 receptor β1 (IL12Rβ1) and IL12Rβ2, is a type I cytokine receptor for IL23. IL23R is comprised of two subunits, the IL12Rβ1 subunit, which is shared with several cytokines, and a subunit that is unique to IL-23. IL23, after binding to IL23R, activates memory T cells and mediates pro-inflammatory activities in part by the production of IL17 through activation of TH17 lymphocytes. IL23R is expressed on T cells, NK cells, dendritic cells, and macrophages. In fact, polymorphisms of the IL23R gene were reported to be associated with susceptibility to inflammatory diseases and autoimmune diseases such as psoriasis, multiple sclerosis, Gravess ophtalmopathy and inflammatory bowel diseases. The IL23R is known to be critically involved in the carcinogenesis of different malignant tumor..jpg)
我公司强烈推荐重组蛋白系列产品，热情期待您的咨询选购重组人分子伴侣辅因子(热休克蛋白70羧基末端相互作用蛋白)(CHIP)(STUB1)价格。
