北京重组小鼠TIM-3(T细胞免疫球蛋白黏蛋白分子3)厂家

特别声明：本产品及我公司所售其他产品均为科研类试剂产品，严禁用于药物、YL及其他非科研用途。

北京百奥莱博专注于生命科学和生物技术领域，致力于为客户提供包括北京重组小鼠TIM-3(T细胞免疫球蛋白黏蛋白分子3)厂家在内的一系列分子生物学试剂产品，并提供一系列相关的技术服务。

名称：北京重组小鼠TIM-3(T细胞免疫球蛋白黏蛋白分子3)厂家
编号：JN1502
规格：10μg|50μg|500μg|1mg
英文名：Recombinant Mouse T cell Immunoglobulin and Mucin Domain-3
品Pai：百奥莱博
产地：北京
本品由我们的哺乳动物细胞表达系统制备而成，目的基因编码的Arg20-Arg191在C端含有His标签。

TIM-3质量控制：＞95%(还原性SDS-PAGE)

TIM-3制剂：冻干品

TIM-3保存：
冻干蛋白置于-20℃以下可长期保存，室温条件下可稳定保存3周。
复溶蛋白溶液可在4～7℃保存2～7天，可分装后置于-20℃保存三个月。

TIM-3复溶：
打开试剂管前请先离心。
复溶浓度推荐大于100μg/ml。
冻干蛋白请溶于ddH2O。
复溶后，请根据用量分装冻存，避免反复冻融。

关于TIM-3 ：
T cell immunoglobulin and mucin domain-3 (TIM3), also called hepatitis A virus cellular receptor 2 (HAVCR2), is a transmembrane glycoprotein of the TIM family of immune regulating molecules and plays an important role in the Th1-mediated immune response. TIM3 is expressed on the Th1 cells, CD8 T-cells, monocytes, and dendritic cells, but not on Th2 cells. TIM3 expressed by monocytes and dendritic cells facilitates phagocytosis of apoptotic cells and up-regulates cross-presentation of apoptotic cell-associated antigens through interaction with phosphatidylserine. Engagement of TIM3 by its ligand galectin-9 induces a range of immunosuppressive functions which enhance immune tolerance and inhibit anti-tumor immunity. Stimulation of TIM3 with an agonistic antibody promotes inflammation through the activation of innate immune cells. TIM3 is also regarded as a potential target molecule for immunotherapy. TIM3 and programmed cell death 1 (PD-1) as two important coinhibitory regulators of T cell responses, have been implicated with the T-cell dysfunction or exhaustion associated with chronic HBV infection including HBV-related HCC.

欲了解更多北京重组小鼠TIM-3(T细胞免疫球蛋白黏蛋白分子3)厂家的品Pai、产地、价格及说明书等产品信息，请致电北京百奥莱博科技有限公司，我们将竭诚为您服务，另外，以下产品正在火爆促销:

·重组人泛素结合酶E2-D1(UBCE2D1)
编号：JN1202
英文名称：Recombinant Human Ubiquitin-conjugating enzyme E2 D1
规格：10μg|50μg|500μg|1mg
本品由我们的大肠杆菌表达系统制备而成，目的基因编码的Met1-Met147在N端带有GST标签。

UBE2D1质量控制：＞95%(还原性SDS-PAGE)

UBE2D1制剂：冻干品

UBE2D1保存：
冻干蛋白置于-20℃以下可长期保存，室温条件下可稳定保存3周。
复溶蛋白溶液可在4～7℃保存2～7天，可分装后置于-20℃保存三个月。

UBE2D1复溶：
打开试剂管前请先离心。
复溶浓度推荐大于100μg/ml。
冻干蛋白请溶于ddH2O。
复溶后，请根据用量分装冻存，避免反复冻融。

关于UBE2D1：
Ubiquitin-conjugating enzyme E2 D1(UBE2D1)belongs to the ubiquitin-conjugating enzyme family. Ubiquitination involves at least three classes of enzymes: ubiquitin-activating enzymes, or E1s, ubiquitin-conjugating enzymes, or E2s, and ubiquitin-protein ligases, or E3s. This enzyme is closely related to a stimulator of iron transport (SFT), and is up-regulated in hereditary hemochromatosis. It also functions in the ubiquitination of the tumor-suppressor protein p53 and the hypoxia-inducible transcription factor HIF1alpha by interacting with the E1 ubiquitin-activating enzyme and the E3 ubiquitin-protein ligases.


北京重组小鼠TIM-3(T细胞免疫球蛋白黏蛋白分子3)厂家关键词：重组小鼠TIM-3,重组小鼠T细胞免疫球蛋白黏蛋白分子3,重组TIM-3,JN1502,重组小鼠TIM-3蛋白

YT006 RNase A (100mg/ml)(不含DNase) Ribonuclease A（DNase free）
SV0951 Bsu DNA 聚合酶，大片段
HR0029 细胞膜蛋白提取试剂盒 Membrane protein extraction kit
BTN90509 包涵体中量纯化试剂盒 Inclusion Body Midiprep Kit
YT360 *离子荧光探针(MQAE) Chloride ion fluorescence probe
SY0274 快速核酸银染试剂盒 Rapid Silver Stain Kit for Nucleic Acid
KFS047 kFluor350标记抗小鼠免疫荧光染色试剂盒 Immunol Fluorescence Staining Kit with kFlour350-Labeled Goat Anti-Mouse IgG
BTN131017 乙酰化牛血清白蛋白 Bovine Serum Albumin, Acetylated
SY0071 Nanog-Luc荧光素酶报告基因质粒 Nanog luciferase reporter plasmid
SY0759 BCIP/NBT显色试剂盒蓝紫色(IHC) BCIP/NBT Alkaline Phosphatase (AP) Substrate Kit For IHC
WE0100 PCR Mix(含染料)(滴瓶装) PCR Mix(With Dye)
SV0298 CviQI限制性内切酶 CviQI Restriction Endonuclease
SY0432 Anit-HA亲和纯化凝胶 Anti-HA Affinity Gel
BTN130904 超级杂交液(Oligo探针) Super hybrid solution(Oligo probe)
YT111 AMCA抗小鼠免疫荧光染色试剂盒 Immunol Fluorence Staining Kit with AMCA-Labeled GoatAnti-Mouse IgG
SV1153 dam 甲基转移酶 Dam methyl transferase
HR0237 组织线粒体提取试剂盒 Tissue mitochondria Extraction Kit
BTN70704B 预染蛋白Marker(43～200kD) Prestained Protein Marker(43-200kD)
北京重组小鼠TIM-3(T细胞免疫球蛋白黏蛋白分子3)厂家关键词：重组小鼠TIM-3,重组小鼠T细胞免疫球蛋白黏蛋白分子3,重组TIM-3,JN1502,重组小鼠TIM-3蛋白


·重组小鼠TREM-2b(髓细胞触发受体2b)(C端带His标签)
编号：JN1535
英文名称：Recombinant Mouse Triggering Receptor Expressed on Myeloid Cells 2b
规格：10μg|50μg|500μg|1mg
本品由我们的哺乳动物细胞表达系统制备而成，目的基因编码的Leu19-Pro168在C端含有His标签。

TREM-2b质量控制：＞95%(还原性SDS-PAGE)

TREM-2b制剂：冻干品

TREM-2b保存：
冻干蛋白置于-20℃以下可长期保存，室温条件下可稳定保存3周。
复溶蛋白溶液可在4～7℃保存2～7天，可分装后置于-20℃保存三个月。

TREM-2b复溶：
打开试剂管前请先离心。
复溶浓度推荐大于100μg/ml。
冻干蛋白请溶于ddH2O。
复溶后，请根据用量分装冻存，避免反复冻融。

关于TREM-2b ：
Triggering receptor expressed on myeloid cells-2 (TREM-2) is a cell surface receptor primarily expressed on macrophages, osteoclasts, microglia and dendritic cells. TREM-2 is one member of the TREM family, inhibiting the releasing of inflammatory mediators, so it is an important in vivo anti-inflammatory receptor. TREM-2 consists of an 18 aa signal sequence, a 153 aa extracellular domain (ECD) with one V-type Ig-like domain, a 21 aa transmembrane (TM) domain, and a 35 aa cytoplasmic tail. A soluble form of TREM-2 (TREM-2b) created by alternate splicing diverges at aa 161. TREM-2 transduces intracellular signals through the adaptor DAP12. After binding of TREM-2 with ligand, the TREM-2/DAP12 (dead-cell-activated-receptor-associated protein)-mediated signal transduction pathway causes a series of intracellular protein tyrosine phosphorylation reactions and enzymatic reactions, which then activate the myeloid cells and participate T cell responses.

我公司生产供应销*(代"售")的重组蛋白正全品类优惠促销，十分期待您的咨询选购北京重组小鼠TIM-3(T细胞免疫球蛋白黏蛋白分子3)厂家。