重组人BH3结构域凋亡诱导蛋白(BID) 重组蛋白
- 品牌:百奥莱博
- 型号:收到货后请置于-20℃
- 产地:北京
- 供应商:北京百奥莱博科技有限公司
- 供应商报价:¥140 - 2440
- 标签:重组人BH3结构域凋亡诱导蛋白(BID) 重组蛋白、重组人BH3结构域凋亡诱导蛋白(BID) 重组蛋白价格、重组人BH3结构域凋亡诱导蛋白(BID) 重组蛋白厂家、Recombinant Human BH3-Interacting Domain Death Agonist、、北京百奥莱博科技有限公司
特别声明:本产品及我公司所售其他产品均为科研类试剂产品,严禁用于药物、YL及其他非科研用途。
重组人BH3结构域凋亡诱导蛋白(BID) 是高品质的重组蛋白产品,由北京百奥莱博供应,用于科研目的生化试验项目,本产品质量好,且极具价格优势,深为用户称道,了解更多重组人BH3结构域凋亡诱导蛋白(BID)等重组蛋白产品请联*(代"系")我司咨询订购。
名称:重组人BH3结构域凋亡诱导蛋白(BID) 重组蛋白
编号:JN1912
规格:10μg|50μg|500μg|1mg
英文名:Recombinant Human BH3-Interacting Domain Death Agonist
品Pai:百奥莱博
产地:北京
本品由我们的大肠杆菌表达系统制备而成,目的基因编码的Met1-Asp195表达纯化得来。
BID/BH3-interacting domain death agonist质量控制:>95%(还原性SDS-PAGE)
BID/BH3-interacting domain death agonist制剂:液体
BID/BH3-interacting domain death agonist保存:收到货后请置于-20℃,可保存6个月,避免反复冻融。
关于BID/BH3-interacting domain death agonist:
BH3-Interacting Domain Death Agonist (BID) is a member of the Bcl-2 protein family which regulates outer mitochondrial membrane permeability. BID is a pro-apoptotic member that causes cytochrome c to be released from the mitochondria intermembrane space into the cytosol. Interaction of Bid with Bak causes altered mitochondrial membrane permeability. BID contains only the BH3 domain, which is required for its interaction with the Bcl-2 family proteins and for its pro-death activity. BID is susceptible to proteolytic cleavage by caspases, calpains, Granzyme B and cathepsins. It is an integrating key regulator of the intrinsic death pathway that amplifies caspase-dependent and caspase-independent execution of neuronal apoptosis. Therefore pharmacological inhibition of BID provides a promising therapeutic strategy in neurological diseases where programmed cell death is prominent, and also offer a new strategy for the treatment of acute renal failure associated with ischemia-reperfusion. BID receives direct inputs from a key regulator of the cell cycle arrest/DNA repair machinery (ATM), and therefore is an excellent candidate to coordinate genotoxic stress responses and apoptotic cell death. BID is a novel pro-apoptosis Bcl-2 family protein that is activated by caspase 8 in response to Fas/TNF-R1 death receptor signals. Deletion of BID inhibits carcinogenesis in the liver, although this genetic alteration promotes tumorigenesis in the myeloid cells. This is likely related to the function of BID to promote cell cycle progression into S phase. BID could be also involved in the maintenance of genomic stability by engaging at mitosis checkpoint..jpg)
更多有关重组人BH3结构域凋亡诱导蛋白(BID) 重组蛋白的价格及使用说明等,请联*(代"系")我们的业务经理王欣女士咨询,我公司还销*(代"售")以下产品:
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重组人BH3结构域凋亡诱导蛋白(BID) 重组蛋白关键词:重组人BH3结构域凋亡诱导蛋白蛋白,重组人BID,JN1912,重组BH3结构域凋亡诱导蛋白.jpg)
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HR0011 植物磷酸化蛋白提取试剂盒 Plant Phosphorylated protein extraction kit
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重组人BH3结构域凋亡诱导蛋白(BID) 重组蛋白关键词:重组人BH3结构域凋亡诱导蛋白蛋白,重组人BID,JN1912,重组BH3结构域凋亡诱导蛋白.jpg)
·重组人Cystatin S(胱抑素S)
编号:JN1675
英文名称:Recombinant Human Cystatin S
规格:10μg|50μg|500μg|1mg
本品由我们的哺乳动物细胞表达系统制备而成,目的基因编码的Ser21-Ala141在C端含有His标签。
Cystatin S质量控制:>95%(还原性SDS-PAGE)
Cystatin S制剂:冻干品
Cystatin S保存:
冻干蛋白置于-20℃以下可长期保存,室温条件下可稳定保存3周。
复溶蛋白溶液可在4~7℃保存2~7天,可分装后置于-20℃保存三个月。
Cystatin S复溶:
打开试剂管前请先离心。
复溶浓度推荐大于100μg/ml。
冻干蛋白请溶于ddH2O。
复溶后,请根据用量分装冻存,避免反复冻融。
关于Cystatin S:
Cystatin-S, also called Cystatin-SA-III or Salivary acidic protein, is usually expressed in submandibular and sublingual saliva but not in parotid saliva(at protein level). This protein, which is phosphorylated at both its N- and C-terminal regions, belongs to the cystatin family. Cystatin-S can function as an inhibitor to papain or ficin, it partially inhibits stem bromelain and bovine cathepsin C..jpg)
北京百莱博科技有限公司是重组蛋白产品的专业生产供应销*(代"售")商,恭候您的咨询选购重组人BH3结构域凋亡诱导蛋白(BID) 重组蛋白。