北京YT846型Survivin抗体价格
- 品牌:百奥莱博
- 型号:-20℃冻存,避光
- 产地:北京
- 供应商:北京百奥莱博科技有限公司
- 供应商报价:¥100 - 2450
- 标签:北京YT846型Survivin抗体价格、北京YT846型Survivin抗体价格价格、北京YT846型Survivin抗体价格厂家、、、北京百奥莱博科技有限公司
特别声明:本产品及我公司所售其他产品均为科研类试剂产品,严禁用于药物、YL及其他非科研用途。
北京百奥莱博主要从事生物试剂的生产和销*(代"售"),产品线涵盖北京YT846型Survivin抗体价格在内的抗体抗原产品,还包括PCR及荧光定量PCR、核酸提取试剂盒类、样本核酸保护试剂、核酸提取、克隆与转化、蛋白纯化、蛋白检测、免疫组化、细胞凋亡与抗体等。
名称:北京YT846型Survivin抗体价格
编号:YT846
规格:>20次
英文名:anti-Survivin antibody
品Pai:百奥莱博
产地:北京
本抗体是用经过适当修饰的人Survivin Ser60附近的一段多肽为抗原制备而成的抗Survivin兔单克隆抗体。本抗体如果用于常规的Western检测,至少可以检测20次。
本Survivin抗体可以检测人、小鼠和大鼠蛋白样品,可以检测细胞内源性的Survivin。
Survivin是一种在胚胎发育和重量细胞中高表达的抗凋亡蛋白。Survivin可以结合并YZCaspase-3,YZ细胞凋亡促进细胞分裂,调控细胞周期G2/M期检验点(checkpoint)。Survivin的Thr34可以被p34 cdc2 kinase磷酸化修饰。Thr34突变的Survivin或Survivin RNAi可以YZ肿瘤生长。
产品组份:
Survivin抗体————20μl
Western一抗稀释液————20ml
抗体参数:
免疫原物种:人
免疫原:人Survivin Ser60附近的一段多肽
克隆性:单克隆
宿主:兔
用途:WB,IP,IC,IHC,IF,FCM
可检测样品:人,小鼠,大鼠
Survivin分子量:16kD
推荐稀释比例:WB(1:1000),IP(1:400),IC(1:400),IHC(1:400),IF(1:1000),FCM(1:400)
注意事项:
1. 在Western实验后,请注意回收稀释的抗体。回收的抗体在进行Western实验时至少可以重复使用10次。稀释后的抗体,包括已经使用过的稀释抗体,4℃保存。
2. 回收后重复使用的抗体,使用方法同新鲜稀释的抗体。如果在重复使用过程中发现抗体出现轻微混浊现象,可以10000g离心1-3分钟,取上清用于后续检测。如果回收的抗体出现明显的絮状物或长霉长菌等情况,则可以考虑废弃该抗体。
3. 对于本抗体,Western检测时一抗要4℃缓慢摇动过夜,如果仅短时间与一抗孵育检测效果较差。
储存条件:-20℃,有效期一年。
更多有关北京YT846型Survivin抗体价格的价格及使用说明等,请联*(代"系")我们的业务经理王欣女士咨询,我公司还销*(代"售")以下产品:
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北京YT846型Survivin抗体价格关键词:Survivin抗体,兔抗人Survivin Ser60附近的一段多肽,人Survivin Ser60附近的一段多肽抗体,YT846
·小鼠抗BAX蛋白抗体
编号:YT682
英文名称:BAX Mouse Monoclonal Antibody
规格:50μl
本品为来源于小鼠的抗BAX蛋白的单克隆抗体
宿主:小鼠
用途:WB,ICC, IHC,FC, IF
交叉反应性:人,小鼠
分子量:21KDa
推荐稀释比例:WB(1:500-1:1000),IF(1:200),IHC(1:200),ICC(1:200),FC(1:50)
克隆性:单克隆抗体
About this Antibody | |
Name | BAX Mouse Monoclonal Antibody |
Category | Monoclonal antibody(mAb); Primary antibody |
Isotype | IgA |
Purification | Peptide affinity purified |
About the Immunogen | |
Immunogen | This antibody is produced by immunizing mice with a synthetic peptide (KLH-coupled) corresponding to N-terminal BAX. |
Gene ID | 581 |
SwissProt | Q07812 |
Synonyms | BAX; BCL2L4 |
Category | Apoptosis |
Background | BAX is a member of the Bcl-2 gene family. Apoptosis regulator BAX promotes apoptosis by binding to and antagonizing the Bcl-2 protein. In healthy mammalian cells, the majority of BAX is found in the cytosol, but upon initiation of apoptotic signaling, Bax undergoes a conformational shift. Upon induction of apoptosis, BAX becomes organelle membrane-associated, and in particular, mitochondrial membrane associated. The expression of BAX is upregulated by the tumor suppressor protein p53, and BAX has been shown to be involved in p53-mediated apoptosis. The p53 protein is a transcription factor that, when activated as part of the cell"s response to stress, regulates many downstream target genes, including BAX. |
About this Antibody | |
Name | MGMT Rabbit Polyclonal Antibody |
Category | Polyclonal antibody(pAb); Primary antibody |
Isotype | IgG |
Purification | Peptide affinity purified |
About the Immunogen | |
Immunogen | This antibody is produced by immunizing rabbits with a synthetic peptide (KLH-coupled) corresponding to MGMT. |
Gene ID | 4255 |
SwissProt | P16455 |
Synonyms | Methylated-DNA-protein-cysteine methyltransferase; EC 2.1.1.63; 6-O-methylguanine-DNA methyltransferase; MGMT |
Category | Cell Cycle / Checkpoint Control |
Background | MGMT (O-6-methylguanine-DNA methyltransferase) is a DNA repair enzyme that participates in a suicide reaction that specifically removes methyl or alkyl groups from the O (6) position of guanine, restoring guanine to its normal form without causing DNA breaks. MGMT protects cells from alkylating toxins, and is an important factor in drug resistance to alkylating therapeutic agents. It is ubiquitously expressed in normal human tissues and is overexpressed in many types of human tumors, but epigenetically silenced in other tumors. MGMT silencing is a marker associated with poor prognosis, but is a good predictive marker for response to alkylating agent chemotherapy. |
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