规格: | 5mg | 产品价格: | 577.5 |
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规格: | 10mg | 产品价格: | 1039.5 |
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规格: | 50mg | 产品价格: | 4620 |
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规格: | 100mg | 产品价格: | 8085 |
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Catalog Number 15132
Molecular Formula C10H12O2 • C4H6O6
Relative Molecular Mass 310.3
Formulation A crystalline solid
λmax 260 nm
Purity ≥98%
Storage -20°C
SMILES OC(C(O)C(O)=O)C(O)=O.C1(C2=CN=CC=C2)CC=CCN1
产品描述
(R,S)-Anatabine is a minor alkaloid produced in plants of the Solanaceae family, including tobacco. The detection of (R,S)-anatabine in urine is used as an indicator of tobacco use, particularly when nicotine-containing products (gum, patches, inhalers, and medications) are also being used. (R,S)-Anatabine increases nicotine self-administration and locomotor activity in rats. Of note, (R,S)-anatabine diminishes amyloid beta (Aβ) production in vitro and in vivo. (R,S)-Anatabine reduces (at 600 µg/ml) the transcription and protein levels of β-secretase, lowering the amount of Aβ1-40 and Aβ1-42 in a dose dependent manner in SHSY-5Y cells. (R,S)-Anatabine also dose dependently inhibits NF-κB activation. (R,S)-Anatabine (tartrate) may be preferable to (R,S)-Anatabine (Item No. 11001) for certain applications and formulations.
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Cayman公司成立于1980年,在过去20多年的发展过程中,始终保持着为科研工作者提供高质、优价研究产品的宗旨。该公司目前可以提供13,138 多种生化和免疫试剂,涉及肿瘤、氧化氮、神经学、凋亡、氧化性损伤、内分泌学等研究领域。非常有特色的检测试剂盒包括类花生酸类物质、游离的生物标志、环核苷、激素及氧化氮等。


温馨提示:不可用于临床ZL。