特别提示:包括重组人FGF-10/KGF-2在内,本公司的所有产品仅可用于科研实验,严禁用于临床YL及其他非科研用途!
产品名称:重组人FGF-10/KGF-2
英文名称:Recombinant Human Keratinocyte Growth Factor-2/FGF-10
产品货号:GS4837
产品规格:5μg
分子量:Approximately 19.1kDa,a single,non-glycosylated polypeptide chain containing 169 amino acids.
储存条件:冷冻(-20℃)
概述
Fibroblast growth factor 10 belongs to the fibroblast growth factor(FGF)family which is involved in a variety of biological processes such as embryonic development,cell growth,morphogenesis,tissue repair,tumor growth and invasion.Like most other FGF family members,FGF-10 also has a heparin-binding domain and it plays an important role in the regulation of embryonic development,cell proliferation and cell differentiation.In addition,FGF-10 may play a role in wound healing and is required for normal branching morphogenesis.Recombinant human FGF-10 contains a 208 amino acids and it shares 92%and 95%amino acid sequence identity with murine and rat FGF-10.Defects in FGF-10 are the cause of autosomal dominant aplasia of lacrimal and salivary glands and lacrimo-auriculo-dento-digital syndrome.
使用说明
This material is offered by Biorab Biotech for research,laboratory or further evaluation purposes.NOT FOR HUMAN USE.
技术规格
外观 |
Sterile Filtered White lyophilized(freeze-dried)powder. |
纯度 |
>97%by SDS-PAGE and HPLC analyses. |
来源 |
Escherichia coli. |
生物活性 |
Fully biologically active when compared to standard.The as determined by thymidine uptake assay using FGF-receptors transfected BaF3 cells is less than 0.5ng/ml,corresponding to a specific activity of>2.0×106 IU/mg. |
成分 |
Lyophilized from a 0.2μmfiltered concentrated solution in 2×PBS,pH 7.4. |
内毒素 |
Less than 1 EU/μg of rHuKGF-2/FGF-10 as determined by LAL method. |
复溶 |
We recommend that this vial be briefly centrifuged prior to opening to bring the contents to the bottom.Reconstitute in sterile distilled water or aqueous buffer containing 0.1%BSA to a concentration of 0.1-1.0mg/mL.Stock solutions should be apportioned into working aliquots and stored at ≤ -20 ℃.Further dilutions should be made in appropriate buffered solutions. |
氨基酸序列 |
LGQDMVSPEA TNSSSSSFSS PSSAGRHVRS YNHLQGDVRW RKLFSFTKYF LKIEKNGKVS GTKKENCPYS ILEITSVEIG VVAVKAINSN YYLAMNKKGK LYGSKEFNND CKLKERIEEN GYNTYASFNW QHNGRQMYVA LNGKGAPRRG QKTRRKNTSA HFLPMVVHS |
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关注
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