特别提示：包括重组人FGF-7/KGF-1在内，本公司的所有产品仅可用于科研实验，严禁用于临床YL及其他非科研用途！
产品名称：重组人FGF-7/KGF-1
英文名称：Recombinant Human Keratinocyte Growth Factor-1/FGF-7
产品货号：GS4385
产品规格：2μg
分子量：Approximately 18.9kDa,a single,non-glycosylated polypeptide chain containing 163 amino acids.
储存条件：冷冻（-20℃）
概述
Human KGF-1 also known as Fibroblast growth factor 7(FGF-7),is encoded by the FGF7 gene.KGF-1 only binds to the b splice form of the tyrosine kinase receptor,FGFR2b/KGFR.Affinity between KGF-1 and its receptor can be increased by heparin or heparin sulfate proteoglycan.FGF-10,also called keratinocyte growth factor 2(KGF-2),shares 51%amino acid sequence identity and similar function to KGF-1,but uses an additional receptor,FGFR2c.KGF-1 plays an important role in the regulation of embryonic development,cell proliferation and cell differentiation.KGF-1 actives on keratinocytes,and exhibits mitogenic activity for epidermal cells,but essentially no activity for fibroblasts.KGF-1 has species crossactive,human KGF-1 shares 96%and 92%amino acid sequence identity with murine and rat FGF-7,respectively.
使用说明
This material is offered by Biorab Biotech for research,laboratory or further evaluation purposes.NOT FOR HUMAN USE.
技术规格
| 外观 |
Sterile Filtered White lyophilized(freeze-dried)powder. |
| 纯度 |
＞96%by SDS-PAGE and HPLC analyses. |
| 来源 |
Escherichia coli. |
| 生物活性 |
Fully biologically active when compared to standard.The as determined by thymidine uptake assay using FGF-receptors transfected BaF3 cells is less than 10ng/ml,corresponding to a specific activity of>1.0×105 IU/mg. |
| 成分 |
Lyophilized from a 0.2μmfiltered solution in 20mMPB,0.5MNaCl,pH 8.0. |
| 内毒素 |
Less than 1 EU/μg of rHuKGF-1/FGF-7 as determined by LAL method. |
| 复溶 |
We recommend that this vial be briefly centrifuged prior to opening to bring the contents to the bottom.Reconstitute in sterile distilled water or aqueous buffer containing 0.1%BSA to a concentration of 0.1-1.0mg/mL.Stock solutions should be apportioned into working aliquots and stored at ≤ -20 ℃.Further dilutions should be made in appropriate buffered solutions. |
| 氨基酸序列 |
CNDMTPEQMA TNVNCSSPER HTRSYDYMEG GDIRVRRLFC RTQWYLRIDK RGKVKGTQEM KNNYNIMEIR TVAVGIVAIK GVESEFYLAM NKEGKLYAKK ECNEDCNFKE LILENHYNTY ASAKWTHNGG EMFVALNQKG IPVRGKKTKK EQKTAHFLPM AIT |
根据您的关注的
重组人FGF-7/KGF-1，Recombinant Human Keratinocyte Growth Factor-1/FGF-7，重组Keratinocyte Growth Factor-1/FGF-7，重组人Keratinocyte Growth Factor-1/FGF-7，FGF-7/KGF-1, Human，您可能还对以下产品有需求：
| 货号 |
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规格 |
| JN0238 |
重组人FGF17(成纤维细胞生长因子17)(带His标签) |
10μg|50μg|500μg|1mg |
| JN0263 |
重组小鼠β-NGF(β神经生长因子) |
10μg|50μg|500μg|1mg |
| JN0334 |
重组人白介素IL-6(白细胞介素6) |
10μg|50μg|500μg|1mg |
| JN0337 |
重组人白介素IL-17A(白细胞介素17A) |
10μg|50μg|500μg|1mg |
| JN0613 |
重组人Nogo-66受体相关蛋白3(NgR3) |
10μg|50μg|500μg|1mg |
| JN0696 |
重组人转录起始因子IIB(TFIIB) |
10μg|50μg|500μg|1mg |
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关注
重组人FGF-7/KGF-1，Recombinant Human Keratinocyte Growth Factor-1/FGF-7，重组Keratinocyte Growth Factor-1/FGF-7，重组人Keratinocyte Growth Factor-1/FGF-7，FGF-7/KGF-1, Human的同时，为您推荐更多您可能感兴趣的产品：
名称：重组人TGFβ1(成纤维细胞生长因子β1)
货号：JN0240
规格：10μg|50μg|500μg|1mg
本品由我们的哺乳动物表达系统制备，目的基因编码的Ala279-Ser390表达纯化而来。
TGFβ-1质量控制：＞95%(还原性SDS-PAGE)。
TGFβ-1制剂：冻干品
TGFβ-1保存：
冻干蛋白可在-20℃长期保存，室温也可稳定保存3周。
复溶蛋白溶液可在4～7℃保存2～7天。
复溶后建议分装冻存在-20℃，可保存3个月，应避免反复冻融。
TGFβ-1复溶：
1、试剂开盖前请先离心。
2、复溶浓度应大于100 μg/ml.
3、冻干蛋白溶于ddH2O中
4、复溶后根据使用量分装保存，避免反复冻融。
关于TGFβ-1：
Transforming Growth Factor β-1 (TGFβ-1) is a secreted protein which belongs to the TGF-β family. TGFβ-1 is abundantly expressed in bone, articular cartilage and chondrocytes and is increased in osteoarthritis (OA). TGFβ-1 performs many cellular functions, including the control of cell growth, cell proliferation, cell differentiation and apoptosis. The precursor is cleaved into a latency-associated peptide (LAP) and a mature TGFβ-1 peptide. TGFβ-1 may also form heterodimers with other TGFβ family members. It has been found that TGFβ-1 is frequently upregulated in tumor cells. Mutations in this gene results in Camurati-Engelmann disease.
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