颅内给药导管，可用来配合动物微量给药渗透压泵Alzet Osmotic Pumps ，埋植与颅骨上，对大鼠、小鼠的颅内（脑不的特定部位）进行持续的微量给药。
ALZET微渗透压泵通过脑输注附件套，进行直接的脑部药物输注。已经有成百上千关于神经科学的文献发表，输注的药物包括生长因子，siRNA，精神药物等。
| ALZET Brain Infusion Kit 1 | ALZET Brain Infusion Kit 2 | ALZET Brain Infusion Kit 3 |
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Order number: 0004760 |
Order number: 0008663 |
Order number: 0008851 |
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Note: all materials in the Kits meet US Pharmacopoeia (USP) Class VI standards for the biocompatibility of medical plastics. Kit materials have been exposed to a sterilizing dose of radiation from a 60Co source. |
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| Brain Infusion Cannula |
Brain Infusion Kit 1
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Brain Infusion Kit 2
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Brain Infusion Kit 3
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Material (tube) |
Stainless steel |
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Gauge (tube) |
28 gauge |
30 gauge |
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Dimensions (steel tube) |
ID = 0.18 mm; OD = 0.36 mm; length below pedestal = 5 mm |
ID = 0.16 mm; OD = 0.31 mm; length below pedestal = 3 mm |
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Penetration depths (adjust using spacers) |
3-5 mm (from skull surface) |
1-3 mm (from skull surface) |
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Material (elbow stop, flange) |
Polycarbonate |
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Side Connector (for catheter attachment) |
0.71 mm (21 gauge) |
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Cannula Design |
Narrow diameter with suture grooves |
Low profile and wide base for skin closure and stability |
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Volume inside tube |
0.32 µl |
0.23µl |
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Height Adjustment Spacers |
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Material |
Polycarbonate |
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Dimensions (height) |
0.5 mm |
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Catheter Tubing |
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Material |
Polyvinylchloride (Medical grade) |
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Length |
15 cm (approx.) |
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Inside diameter |
0.69 mm (± 0.08) |
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Outside diameter |
1.14 mm (± 0.08) |
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Volume per 15 cm |
56 µl (3.7 µl/cm) |
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根据研究需要，还可以选择 植入式缓释给药胶囊配合KIT导管 埋入大小鼠皮下和颅骨上，对脑部进行持续的缓释给药：
ALZET微渗透压泵通过脑输注附件套，进行直接的脑部药物输注。已经有成百上千关于神经科学的文献发表，输注的药物包括生长因子，siRNA，精神药物等。
PE聚乙烯实验导管和Vinyl乙烯基实验导管
ALZET微渗透泵通过实验导管，可将物质输注到动静脉循环，脑部，任何器官腔内，或固体组织内。
PE管及VINYL管技术参数:
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ALZET微渗透压泵的优点 |
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Alzet Osmotic Pumps符合 USP YL用塑胶材料生物相容性标准，适合植入实验动物体內，针对特定部位給药，或將药剂用导管导入作用部位, 例如: 脊髓及颅腔内, 血管内, 肝脏, 及其它脏器肿瘤和创伤处。
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