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5-Hole Box, 5-CSRT

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The 5-hole box can be used to run 5-choice serial reaction time task (5-CSRT).
The 5-CSRT has been used for measuring effects of systemic drug treatments and also central manipulations such as neurochemical lesions on various aspects of attentional control,including sustained, selective and divided attention – and is relevant to the definition of neural systems of attention and applications to human disorders such as attention deficit/hyperactivity disorder (ADHD) and Alzheimer’s disease.

The 5-CSRT is implemented in a specially designed operant chamber with multiple response locations (’five-hole box’) using food reinforcers to maintain performance on baseline sessions (about 100 trials) at criterion levels of accuracy and trials completed. The 5-CSRT can be used for measuring various aspects of attentional control over performance with its main measures of accuracy, premature responding, correct response latencies and latency to collect earned food pellets.


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