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Recombinant Rhesus Macaque Flt-3 Ligand

产品信息
  • Recombinant Rhesus Macaque Flt-3 Ligand
    产品编号 产品名称 产品包装 产品价格
    LM5885-1mg Recombinant Rhesus Macaque Flt-3 Ligand 1mg 27053.00
     
    Species Gene ID Accession Source Length MW Tag
    Rhesus Macaque 719239 LM9Z6V7 E. coli 159aa 18kDa
     
    About this Antibody
    Name Recombinant Rhesus Macaque Flt-3 Ligand (Recombinant Rhesus Macaque Fms-related Tyrosine Kinase 3 Ligand; rRhFlt-3L);重组恒河猴Fms相关酪氨酸激酶3配体
    Synonyms Fms-related tyrosine kinase 3 ligand; FLT3LG
    Purity >97% by SDS-PAGE and HPLC analyses.
    Biological Activity Fully biologically active when compared to standard. The as determined by a cell proliferation assay using human Aml5 cells is less than 1.0ng/ml, corresponding to a specific activity of >1.0×106IU/mg.
    Physical Appearance Sterile Filtered White lyophilized (freeze-dried) powder.
    Formulation Lyophilized from a 0.2μm filtered solution in PBS, pH7.4.
    Endotoxin Less than 1EU/μg of rRhFlt-3L as determined by LAL method.
    Reconstitution We recommend that this vial be briefly centrifuged prior to opening to bring the contents to the bottom. Reconstitute in sterile distilled water or aqueous buffer containing 0.1% BSA to a concentration of 0.1-1.0mg/ml. Stock solutions should be apportioned into working aliquots and stored at ≤-20℃. Further dilutions should be made in appropriate buffered solutions.
    Category Cytokine
    Background Flt-3 ligand (FL) is a recently identified hematopoietic cytokine whose activities are mediated by binding to the transmembrane glycoprotein Flt-3. Flt-3 was first discovered as a member of the class III subfamily of receptor tyrosine kinases (RTK) whose expression among hematopoietic cells was found to be restricted to highly enriched stem/progenitor cell populations. Additionally, class III RTKs include the receptors from SCF, M-CSF and PDGF. Not surprisingly, Flt-3 ligand is also structurally related to M-CSF and SCF. All three cytokines have been shown to exist both as type I transmembrane proteins and as soluble proteins. The predominant human FL isoform is a transmembrane protein that can undergo proteolytic cleavage to generate a soluble form of the protein. FL has been shown to synergize with a wide variety of hematopoietic cytokines to stimulate the growth and differentiation of early hematopoietic progenitors.
    Amino Acid Sequence TQDCSFQHSP ISSDFAVKIR ELSDYLLQDY PVTVPSNLQD EELCGALWRL VLAQRWMERL KTVAGSKMQG LLERVNTEIH FVTKCAFQHP PSCLRFVQTN ISRLLQETSE QLVALKPWIT RQNFSRCLEL QCQPDSSTLP PPRSPGALEA TALTAPQRP
    包装清单:
    产品编号 产品名称 包装
    LM5885-2μg Recombinant Rhesus Macaque Flt-3 Ligand 2μg
    LM5885-10μg Recombinant Rhesus Macaque Flt-3 Ligand 10μg
    LM5885-100μg Recombinant Rhesus Macaque Flt-3 Ligand 100μg
    LM5885-1mg Recombinant Rhesus Macaque Flt-3 Ligand 1mg
    - 说明书 1
    保存条件:
           -20℃或更低温度保存,至少一年有效。由于蛋白的每次冻融均会引起部分失活,所以首次配制成相应浓度的储存液后(请根据产品简介中Reconstitution一栏的信息配制储存液),须分装后-20℃或更低温度冻存,以避免反复冻融。
    注意事项:
           由于有些塑料管壁对某些蛋白有较强的吸附作用,溶液中的蛋白很容易粘附在管壁上,并且粘附后的蛋白很难与管壁分离。而载体蛋白(Carrier protein,如0.1% BSA等)的主要作用是预先封闭塑料管壁上的蛋白结合位点,使细胞因子或重组蛋白不会粘附于管壁。所以一定要使用产品简介中Reconstitution一栏的信息配制储存液。
           本产品仅限于专业人员的科学研究用,不得用于临床诊断或ZL,不得用于食品或药品,不得存放于普通住宅内。
           为了您的安全和健康,请穿实验服并戴一次性手套操作。


     
    温馨提示:不可用于临床ZL。
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