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SMPH试剂,双功能交联剂,脂溶-NH反应基团

产品信息
  • 产品名称:SMPH
    英文名称:(succinimidyl-6-((b-maleimidopropionamido)hexanoate)
    简介:SMPH crosslinker (Succinimidyl-6-[ß-maleimidopropionamido]hexanoate) is a water insoluble, heterobifunctional protein crosslinker with a non-cleavable spacer arm length of 14.3 angstroms. The SMPH crosslinking reagent has maleimide groups which are reactive to thiols (sufhydryls) and its NHS ester groups react with amines at pH 6.5-7.5 and 7-9, respectively

    General description
    SMPH is a heterobifunctional crosslinker with N-hydroxysuccinimide (NHS) ester and maleimide groups that allow covalent conjugation of amine- and sulfhydryl-containing molecules. NHS esters react with primary amines at pH 7-9 to form amide bonds, while the maleimides react with sulfhydryl groups at pH 6.5-7.5 to form stable thioether bonds. In aqueous solutions, hydrolytic degradation of the NHS ester is a competing reaction whose rate increases with pH. The maleimide group is more stable than the NHS-ester group but will slowly hydrolyze and also lose its reaction specificity for sulfhydryls at pH values greater than 7.5. For these reasons, conjugation experiments involving this type of heterobifunctional crosslinker are usually performed at pH 7.2-7.5, with the NHS-ester (amine-targeted) reaction being accomplished before or simultaneous with the maleimide (sulfhydryl-targeted) reaction.

    外观:白色粉末
    Molecular Weight: 379.4
    分子式:C17H21N3O7
    溶解:DMSO or DMF
    Alternative Name: Succinimidyl-6-[βmaleimidopropionamido] hexanoate
    纯度:98%+
    保存:-20
    厂家:西安瑞禧生物科技有限公司

    供应美国双功能交联剂(SMCC,Sulfo-SANPAH,PDPH,LC-SPDP,ANB-NOS)
    我公司提供美国Proteochem交联剂产品,其中包括SMCC,LC-SPDP,BS3,Sulfo-EGS,NHS-Biotin,Biotin-HPDP,Sulfo-NHS-Acetate,NHS-SS-Biotin等等产品试剂。
    产品列表:
    SMCC,CAS:64987-85-5
    Sulfo-SMCC,CAS:92921-24-9
    Sulfo-SANPAH,CAS:102568-43-4
    SMPH
    PDPH
    Sulfo-MBS
    LC-SPDP
    Sulfo-LC-SPDP
    MBS,CAS:58626-38-3
    SPDP,CAS:68181-17-9
    SIA,CAS:39028-27-8
    SBA,CAS:42014-51-7
    SMPB,CAS:79886-55-8
    BMPS,CAS:55750-62-4
    EMCS,CAS:55750-63-5
    GMBS,CAS:80307-12-6
    ANB-NOS,CAS:60117-35-3
    BS3,CAS:82436-77-9
    DSS,CAS:68528-80-3
    DSG,CAS:79642-50-5
    DSP,CAS:57757-57-0
    DTSSP,CAS:81069-02-5
    Sulfo-EGS,CAS:167410-92-6
    EGS,CAS:70539-42-3
    DST,CAS:62069-75-4
    Sulfo-NHS,CAS:106627-54-7
    Sulfo-NHS-Acetate,CAS:152305-87-8
    Sulfo-NHS-Biotin,CAS:119616-38-5
    NHS-Biotin,CAS:35013-72-0
    Sulfo-NHS-LC-Biotin,CAS:127062-22-0
    NHS-LC-Biotin,CAS:72040-63-2
    Sulfo-NHS-SS-Biotin,CAS:325143-98-4
    NHS-SS-Biotin,CAS:142439-92-7
    Biotin Hydrazide,CAS:66640-86-6
    Biotin-HPDP,CAS:129179-83-5
    Iodoacetyl-LC-Biotin,CAS:93285-75-7


    以上资料源于西安瑞禧生物科技有限公司

    如有其他信息或产品信息咨询请致电我们:029-86354885   13309186942张惠宁
    西安瑞禧生物科技有限公司
    Xi'an ruixi Biological Technology Co;Ltd


     
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