mGluR1 Antagonist Explorer Kit

mGluR1 Antagonist Explorer KitA Screening Package of mGluR1 Antagonists Economically Priced
Cat #: EK-250
13 Vials

mGluR1 is predominantly expressed in nervous tissue although expression in several non-neural cell types has also been described. In the brain it is highly expressed in the hippocampus, cerebellum, olfactory bulb and thalamus.

The mGluR1 receptor is involved in several physiological processes such as neuronal development, induction of long-term potentiation (LTP) and depression (LTD) as well as in pathological disorders such as brain trauma, chronic pain, Parkinson’s and Huntington’s disease.

Alomone Labs is pleased to offer the mGluR1 Antagonist Explorer Kit (#EK-250). The Explorer Kit contains mGluR1 antagonists, ideal for screening purposes.

• Compounds
• References

Product Name	Cat #	Size
A-794278	A-435	1 x 5 mg
A-850002	A-390	1 x 5 mg
CFMTI	C-365	1 x 5 mg
CPCCOEt	C-370	1 x 5 mg
DM-PPP	D-255	1 x 5 mg
EM-TBPC	E-165	1 x 5 mg
FPTQ	F-185	1 x 5 mg
FTIDC	F-190	1 x 5 mg
JNJ 16259685	J-110	1 x 5 mg
LY 456236 hydrochloride	L-235	1 x 5 mg
LY456066	L-240	1 x 5 mg
MK-5435	M-265	1 x 5 mg
NPS 2390	N-340	1 x 5 mg

References 

1. Dhami, G.K. and Ferguson, S.S. (2006) Pharmacol. Ther. 111, 260.
2. Ferraguti, F. and Shigemoto, R. (2006) Cell Tissue Res. 326, 483.
3. Kew, J.N. and Kemp, J.A. (2005) Psychopharmacol. (Berl.) 179, 4.