北京重组人VEGFR1(FLT1)(血管内皮生长因子受体1)说明书

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名称：北京重组人VEGFR1(FLT1)(血管内皮生长因子受体1)说明书
英文名：Recombinant Human Vascular Endothelial Growth Factor Receptor 1
规格：10μg|50μg|500μg|1mg
产地：国产|进口
品Pai：百奥莱博
本品由我们的哺乳动物细胞表达系统制备而成，目的基因编码的Ser27-Asn756在C端带有Fc标签。

VEGFR1/FLT1质量控制：＞95%(还原性SDS-PAGE)

VEGFR1/FLT1制剂：冻干品

VEGFR1/FLT1保存：
冻干蛋白置于-20℃以下可长期保存，室温条件下可稳定保存3周。
复溶蛋白溶液可在4～7℃保存2～7天，可分装后置于-20℃保存三个月。

VEGFR1/FLT1复溶：
打开试剂管前请先离心。
复溶浓度推荐大于100 μg/ml。
冻干蛋白请溶于ddH2O。
复溶后，请根据用量分装冻存，避免反复冻融。

关于VEGFR1/FLT1：
Human Vascular endothelial growth factor receptor 1(VEGFR-1, FLT-1) is a member of the the class III subfamily of receptor tyrosine kinases (RTKs) and Tyr protein kinase family and CSF-1/PDGF receptor subfamily. VEGFR-1 is widely expressed in human tissues including normal lung, placenta, liver, kidney, heart and brain tissues. It is specifically expressed in most of the vascular endothelial cellsand peripheral blood monocytes. VEGFR-1 contains seven Ig-like C2-type domains and one protein kinase domain. VEGFR-1is an essential receptor tyrosine kinase and plays an important role in theregulation of VEGF family-mediated vasculogenesis, angiogenesis, and lymphangiogenesis. It is also mediators of neurotrophic activity and regulators of hematopoietic development.VEGFR-1 is a receptor for VEGF, VEGFB and PGF. It has a tyrosine-protein kinase activity. Tyrosine-protein kinase that acts as a cell-surface receptor for VEGFA, VEGFB and PGF.It may play an essential role as a negative regulator of embryonic angiogenesis by inhibiting excessive proliferation of endothelial cells and promote endothelial cell proliferation, survival and angiogenesis in adulthood. Its function in promoting cell proliferation seems to be cell-type specific. VEGFR-1 can also promote PGF-mediated proliferation of endothelial cells, proliferation of some types of cancer cells, but does not promote proliferation of normal fibroblasts (in vitro).

北京重组人VEGFR1(FLT1)(血管内皮生长因子受体1)说明书正在火爆，除此之外，为您推荐下别产品：

·重组小鼠β细胞素(Btc)
编号：JN1299
英文名称：Recombinant Mouse Betacellulin
规格：10μg|50μg|500μg|1mg
本品由我们的大肠杆菌表达系统制备而成，目的基因编码的Asp32-Gln118在N端含有His标签。

Btc质量控制：＞95%(还原性SDS-PAGE)

Btc制剂：冻干品

Btc保存：
冻干蛋白置于-20℃以下可长期保存，室温条件下可稳定保存3周。
复溶蛋白溶液可在4～7℃保存2～7天，可分装后置于-20℃保存三个月。

Btc复溶：
打开试剂管前请先离心。
复溶浓度推荐大于100 μg/ml。
冻干蛋白请溶于ddH2O。
复溶后，请根据用量分装冻存，避免反复冻融。

关于Btc：
Mouse Betacellulin is a single type I membrane protein which belongs to the EGF family of cytokines. EGF family has many members including EGF, TGF-a, Amphiregulin, HB-EGF, Epiregulin, Tomoregulin and the Neuregulins. Betacellulin is characterised by a six-cysteine consensus motif that forms three intra-molecular disulfide bonds crucial for binding the ErbB receptor family. Betacellulin is expressed in several tissues and tumor cells including kidney, uterus, liver, pancreas and small intestine. Betacellulin binds and activates ErbB-1 and ErbB-4 homodimers. Betacellulin is thought to play a role in the differentiation of pancreatic beta cells.Human and mouse mature BTC protein are 80% identical at the amino acid sequence level. Betacellulin is involved in many biological processes such as stimulating gastrointestinal growth. It is proteolytically processed from a larger membrane-anchored precursor and is a potent mitogen for a wide variety of cell types.


北京重组人VEGFR1(FLT1)(血管内皮生长因子受体1)说明书关键词：JN1380,重组人VEGFR1蛋白,重组人FLT1,重组人血管内皮生长因子受体1

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北京重组人VEGFR1(FLT1)(血管内皮生长因子受体1)说明书关键词：JN1380,重组人VEGFR1蛋白,重组人FLT1,重组人血管内皮生长因子受体1

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