1-​(2-​Iodoethyl)​-​2-​octylbenzene

产品：1-​(2-​Iodoethyl)​-​2-​octylbenzene
分子式：C16H25I
分子量：344.27
性状外观:No Data Available
溶点：No Data Available
溶解性:No Data Available

1-​(2-​Iodoethyl)​-​2-​octylbenzene is an impurity of Fingloimod (F805000), also known as FTY720. FTY720 is a derivative of ISP-1 (myriocin), a fungal metabolite of the Chinese herb Iscaria sinclarii as well as a structural analogue of Sphingosine. FTY720 is a novel immune modulator that prolongs allograft transplant survival in numberour models by inhibiting lymphocyte emigration from lymphoid organs. FTY720 us reported to be phosphorylated by sphingosine kinase to FTY720-P, which has been shown to potently stimulate GTPgS binding activity in S1P-transfected CHO cells (EC50 = 210 pM, 4.9 nM, 4.3 nM, and 1 nM for S1P1, S1P3, S1P4 and S1P5, respectively).

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