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β-Secretase inhibitor b-SECRETASE INHIBITOR

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  • β-Secretase inhibitor
    b-SECRETASE INHIBITOR
    Product Number S 4562 Storage Temperature –20 °C (KTEEISEVN [Statine] VAEF; Lys-Thr-Glu-Glu-Ile-SerGlu-Val-Asn-[Statine]-Val-Ala-Glu-Phe-OH)) Product Description Appearance: White Powder Molecular Formula: C73H118N16O27 Formula Weight: 1651.8 Purity: >97 % by HPLC. A b-secretase inhibitor.1 A key event in Alzheimer’s disease is the sequential proteolytic cleavage of the amyloid protein from the amyloid protein precursor (APP) by b- and g-secretase. b-secretase (BACE), a transmembrane aspartyl protease cleaves the APP to yield the N terminus of the amyloid b peptide. Whereas, g-secretase cleaves the C terminus. Accumulation of the amyloid b peptides results in neuritic plaques in brain parenchy
    温馨提示:不可用于临床ZL。
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