小鼠抗人转甲状腺素蛋白抗体/TTR Antibody
- 产地：福建 厦门市
- 供应商：厦门慧嘉生物科技有限公司
- 供应商报价： 电议
- 标签：小鼠抗人转甲状腺素蛋白抗体/TTR Antibody,小鼠抗人转甲状腺素蛋白抗体/TTR Antibody价格,小鼠抗人转甲状腺素蛋白抗体/TTR Antibody厂家
产品库
| Catalogue Number | ANT-003 |
| Synonyms | Transthyretin, ATTR, Prealbumin, TBPA, TTR, PALB, HsT2651. |
| Type | Mouse Anti Human Monoclonal. |
| Introduction | Transthyretin (TTR) is a circulating and abundant tetramer, which functions as a carrier protein of thyroid hormone and retinol binding protein. It is primarily produced in the liver, but also in the brain and eye. Mutations in the TTR gene cause the protein to dissociate into monomers that after misfolding assemble into amyloid fibrils deposits in a variety of organs. TTR is also the only gene known to be associated with familial TTR amyloidosis. The diseases that originate from mutations in the TTR gene include amyloidotic polyneuropathy, euthyroid hyperthyroxinaemia, amyloidotic vitreous opacities, cardiomyopathy, oculoleptomeningeal amyloidosis, meningocerebrovascular amyloidosis, carpal tunnel syndrome, etc. |
| Clone | PAT7B2AT. |
| Physical Appearance | Sterile filtered colorless solution. |
| Immunogen | Anti-human TTR mAb, is derived from hybridization of mouse F0 myeloma cells with spleen cells from BALB/c mice immunized with recombinant human TTR amino acids 21-147 purified from E. coli. |
| Ig Subclass | Mouse IgG1 heavy chain and κ light chain. |
| Purification Method | TTR antibody was purified from mouse ascitic fluids by protein-G affinity chromatography. |
| Protein formulation | 1mg/ml containing PBS, pH-7.4, & 0.1% Sodium Azide. |
| Storage Procedures | For periods up to 1 month store at 4°C, for longer periods of time, store at -20°C. Prevent freeze thaw cycles. |
| Stability / Shelf Life | 12 months at -20°C. 1 month at 4°C. |
| Applications | TTR antibody has been tested by ELISA and Western blot analysis to assure specificity and reactivity. Since application varies, however, each investigation should be titrated by the reagent to obtain optimal results. Recommended dilution range for Western blot analysis is 1:500 ~ 3000. Recommended starting dilution is 1:500. |
| Usage | ProSpecs products are furnished for LABORATORY RESEARCH USE ONLY. The product may not be used as drugs, agricultural or pesticidal products, food additives or household chemicals. |
