产品库
登录
首页 找仪器 社区 百科 新品 供应商 品牌 应用 资料 仪企号 展会 标准 求购 招中标

重组人组胺N-甲基转移酶/HNMT Human

产品信息
重组人组胺N-甲基转移酶/HNMT Human
产品编号:ENZ-402 产品名称:重组人组胺N-甲基转移酶/HNMT Human 产品规格:5ug/20ug/1mg
Catalogue NumberENZ-402
Synonyms HMT, HNMT-S1, HNMT-S2, HNMT, Histamine N-methyltransferase.
Introduction HNMT is located in the cytosol and uses S-adenosyl-L-methionine as the methyl donor. In the mammal’s brain,N(tau)-methylation controls the neurotransmitter activity of histamine since diamine oxidase is not located in the central nervous system. A well known genetic polymorphism influences the activity levels of HNMT gene product in red blood cells. HNMT inactivates histamine by n-methylation. HNMT is involved in degrading histamine and in regulating the airway response to histamine. Histamine is involved in regulation and modulation of immune response through the stimulation of four distinct subtypes of receptors, H1, H2, H3, and H4, that present on the target cells. Histamine is inactivated by the histamine-metabolizing enzyme HNMT in bronchus, kidney, and the central nervous system.
Description HNMT Human Recombinant fused to 36 amino acid His Tag at N-terminal produced in E.Coli is a single, non-glycosylated, polypeptide chain containing 328 amino acids (1-292) and having a molecular mass of 37 kDa.

The HNMT is purified by proprietary chromatographic techniques.
Source Escherichia Coli.
Physical Appearance Sterile Filtered clear colorless solution.
Formulation The HNMT solution contains 20mM Tris-HCl pH-8 and 10% glycerol.
Stability HNMT Recombinant Human although stable at 4°C for 30 days, should be stored desiccated below -20°C for periods greater than 30 days.

Please avoid freeze-thaw cycles.
Amino Acid Sequence MRGSHHHHHH GMASMTGGQQ MGRDLYDDDD KDRWGSMASS MRSLFSDHGK YVESFRRFLN HSTEHQCMQE FMDKKLPGII GRIGDTKSEI KILSIGGGAG EIDLQILSKV QAQYPGVCIN NEVVEPSAEQ IAKYKELVAK TSNLENVKFA WHKETSSEYQ SRMLEKKELQ KWDFIHMIQM LYYVKDIPAT LKFFHSLLGT NAKMLIIVVS GSSGWDKLWK KYGSRFPQDD LCQYITSDDL TQMLDNLGLK YECYDLLSTM DISDCFIDGD ENGDLLWDFL TETCNFNATA PPDLRAELGK DLQEPEFSAK KEGKVLFNNT LSFIVIEA.
Purity Greater than 95.0% as determined by SDS-PAGE.
Usage ProSpecs products are furnished for LABORATORY RESEARCH USE ONLY. The product may not be used as drugs, agricultural or pesticidal products, food additives or household chemicals.

信息声明：本产品供应信息由仪器网为您整合，供应商为（厦门慧嘉生物科技有限公司），内容包括 （ 重组人组胺N-甲基转移酶/HNMT Human）的品牌、型号、技术参数、详细介绍等；如果您想了解更多关于 （ 重组人组胺N-甲基转移酶/HNMT Human）的信息，请直接联系供应商，给供应商留言！
供应商产品推荐
    您可能感兴趣的产品