Introduction:
SARS Coronavirus is an enveloped virus containing three outer structural proteins, namely the membrane (M), envelope (E), and spike (S) proteins. Spike (S)-glycoprotein of the virus interacts with a cellular receptor and mediates membrane fusion to allow viral entry into susceptible target cells. Accordingly, S-protein plays an important role in virus infection cycle and is the primary target of neutralizing antibodies.
Description:
The E.Coli derived 38 kDa mosaic protein contains the N-terminal section of the Spike protein 12-53, 90-115, 171-203 amino acids immunodominant regions.
Purification Method:
SARS Mosaic protein was purified by proprietary chromatographic technique.
Purity:
SARS Mosaic Protein is >95% pure as determined by 10% PAGE (coomassie staining).
Formulation:
25mM Tris-HCl, 0.4% sarcosyl, 0,25% Triton –100 and 50% glycerol.
Storage:
SARS Mosaic protein is shipped at ambient temperature. Upon arrival, store at -200C.
Stability:
Five year frozen, 6 month at +40C.
Specificity:
SARS Mosaic protein is Immunoreactive with sera of SARS-infected individuals.
Applications:
SARS Mosaic antigen is suitable for ELISA and Western blots, excellent antigen for detection of SARS with minimal specificity problems.
Usage:
ProSpec's products are furnished for LABORATORY RESEARCH USE ONLY. The product may not be used as drugs, agricultural or pesticidal products, food additives or household chemicals. | 
