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Dolutegravir Sodium Salt,C20H18F2N3NaO5

产品信息
  • 分子式:C20H18F2N3NaO5;分子量:441.36;外观:Pale Yellow to Green Solid;溶解性:DMSO (Slightly, Heated);别名:Dolutegravir sodium; GSK 1349572A; N-[(2,4-Difluorophenyl)methyl]-3,4,6,8,12,12a-hexahydro-7-hydroxy-4-methyl-6,8-dioxo-2H-pyrido[1',2':4,5]pyrazino[2,1-b][1,3]oxazine-9-carboxamide Sodium Salt;熔点:>300ºC;应用:Dolutegravir is a second generation HIV-1 integrase strand transfer inhibitor. Dolutegravir is currently in Phase III clinical trials for the treatment of HIV infection. Dolutegravir has been shown to potently inhibit HIV replication in cells such as peripheral blood mononuclear cells (PBMCs), MT-4 cells and CIP4 cells infected with a self-inactivating PHIV lentiviral vector.;储存温度:Hygroscopic, -20°C Freezer, Under inert atmosphere。
    温馨提示:不可用于临床ZL。
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