phospho-AMPK alpha-1/PRKAA1(Thr198) Antibody
Cat#:PL0301188
Isotype:Rabbit Polyclonal IgG
Immunogen:PhosphoPeptide derived from Hu AMPK alpha 1 around the phosphorylation site of Thr198(isoform 2)/Thr183(isoform 1).
Purification: Immunogen affinity purified
Storage Buffer: PBS, pH 7.4(1%BSA and 0.1% Sodium azide)
Background:
The protein encoded by this gene belongs to the ser/thr protein kinase family. It is the catalytic subunit of the 5'-prime-AMP-activated protein kinase (AMPK). AMPK is a cellular energy sensor conserved in all eukaryotic cells. The kinase activity of AMPK is activated by the stimuli that increase the cellular AMP/ATP ratio. AMPK regulates the activities of a number of key metabolic enzymes through phosphorylation. It protects cells from stresses that cause ATP depletion by switching off ATP-consuming biosynthetic pathways. Alternatively spliced transcript variants encoding distinct isoforms have been observed.
Alternate Names:
phospho-AMPK alpha-1(Thr198)(isoform 2); phospho-AMPK alpha-1(Thr183)(isoform 1); AMPK alpha 1; 5 AMP activated protein kinase alpha 1catalytic subunit; 5 AMP activated protein kinase catalytic alpha 1 chain; 5' AMP activated protein kinase catalytic subunit alpha 1; AAPK1; acetyl CoA carboxylase kinase; AI194361 antibody AI450832; AL024255; AMP -activate kinase alpha 1 subunit; AMP-activated protein kinase, catalytic, alpha -1; AMPK 1; AMPK alpha 1 chain; AMPK antibody AMPK1; AMPKa1; AMPKalpha1;C130083N04Rik; cb116 antibody EC 2.7.11.1; HMG CoA reductase kinase; hormone sensitive lipase kinase; im:7154392 antibody kinase AMPK alpha1; MGC33776;MGC57364 antibody PRKAA 1; PRKAA1;Protein kinase AMP activated alpha 1 catalytic subunit; SNF1-like protein AMPK; wu:fa94c10; AAPK1_Hu.
Specificity Reaction:Hu, Mo, Rat, Chi, Dog, Pig, Cow, Hor, Sheep,
Application Notes:WB: 1:100-500 E: 1:500-1000 IHC: 1:100-500 IF: 1:100-500
Storage :
Store at –20ºC for one year. Avoid repeated freeze-thaw cycles. At 4ºC for 2-3 weeks after reconstituted.
This product for research use only, not for use in humans, therapeutic or diagnostic procedures.
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