Recombinant Human Synaptosomal-associated protein 23kDaSynonyms SNAP23A, SNAP23B, HsT17016, Synaptosomal-associated protein 23, Vesicle-membrane fusion protein SNAP-23, SNAP23.
Introduction SNAP23 is a non-neuronal SNAP25 protein homologue and a target SNARE ubiquitously expressed on the plasma membrane and other intracellular membranes. SNAP23 is involved in exocytotic membrane fusion in most cells that do not express SNAP-25. SNAP23 is an essential component of the high affinity receptor for the general membrane fusion machinery and an crucial regulator of transport vesicle docking and fusion. SNAP23 is phosphorylated in platelets through cell activation during a protein kinase C-related mechanism at two or more sites. SNAP23, the ubiqitously expressed homologue of SNAP25, interacts directly with ubiquitous kinesin heavy chain (uKHC). SNAP-23 is expressed in human eosinophils and is a candidates for association with VAMP-2 during docking, which is followed by exocytosis.
Recombinant Human Synaptosomal-associated protein 23kDaDescription SNAP23 Human Recombinant produced in E.Coli is a single, non-glycosylated polypeptide chain containing 211 amino acids and having a molecular mass of 23.3 kDa.
Source Escherichia Coli.
Physical Appearance Sterile Filtered colorless solution.
Formulation The protein solution contains 20mM Tris-HCl pH-8.
Stability SNAP23 although stable 4°C for 4 weeks, should be stored desiccated below -18°C.
For long term storage it is recommended to add a carrier protein (0.1% HSA or BSA).
Please prevent freeze-thaw cycles.
Recombinant Human Synaptosomal-associated protein 23kDaAmino Acid Sequence MDNLSSEEIQ QRAHQITDES LESTRRILGL AIESQDAGIK TITMLDEQKE QLNRIEEGLD QINKDMRETE KTLTELNKCC GLCVCPCNRT KNFESGKAYK TTWGDGGENS PCNVVSKQPG PVTNGQLQQP TTGAASGGYI KRITNDARED EMEENLTQVG SILGNLKDMA LNIGNEIDAQ NPQIKRITDK ADTNRDRIDI ANARAKKLID S.
Purity Greater than 90.0% as determined by SDS-PAGE.
Recombinant Human Synaptosomal-associated protein 23kDaUsage CHI's products are furnished for LABORATORY RESEARCH USE ONLY. The product may not be used as drugs, agricultural or pesticidal products, food additives or household chemicals.
