一步法质粒 DNAout 2.050 次说明书
- 产地:上海市
- 供应商:上海一研生物科研有限公司
- 供应商报价:面议
- 标签:一步法质粒 DNAout 2.050 次说明书
一步法质粒 DNAout 2.050 次价格公司提供的RNA/DNA 提取产品齐全,价格优惠,质量保证,欢迎广大科研用户订购!
一步法质粒 DNAout 2.050 次价格的详细介绍:
一步法质粒 DNAout 2.050 次价格
1 柱式DNA提取系列产品
2 柱式RNA提取系列(包括动物,血液,植物,细菌RNA提取)
3 5分钟超快DNA电泳液
4 一步式质粒DNA提取系列产品
5 “绿如蓝”DNA染料
6 固相RNase清除剂
一步法质粒 DNAout 2.050 次价格公司的产品目前有下面10个系列,5000余种产品
1、RNA纯化系列产品
2、DNA纯化系列产品
3、电泳及回收系列产品
4、探针标记及检测系列产品
5、核酸扩增系列产品
6、克隆表达系列产品
7、基因组研究系列产品
8、蛋白质研究系列产品
9、细胞生物学研究系列产品
10、即用型溶液、质粒库、菌种库等等
intended for research use only, not for use in human, therapeutic or diagnostic applications.
产品介绍 Cellular signaling by G-proteins is down-regulated by GTPase-activating proteins (GAPs), which increase the rate of GTP hydroylsis. The GTPase regulator associated with focal adhesion kinase (GRAF) has GAP activity toward Rho A and Cdc42, but not Rac1. GRAF is ubiquitously expressed with high levels in heart and brain. Expression of GRAF causes clearing of stress fibers and formation of long actin based filopodial-like extensions. Fusion of MLL with GRAF, MLL/GRAF, is included in a rare genetic subgroup of acute myeloid leukemia (AML) cases.
Function : GTPase-activating protein for RHOA and CDC42.
Subunit : Interacts with NYAP1, NYAP2 and MYO16 (By similarity). Binds to the C-terminus of PTK2/FAK1.
Subcellular Location : Cell junction; focal adhesion. Cytoplasm; cytoskeleton. Colocalizes with actin stress fibers and cortical actin structures.
DISEASE : Defects in ARHGAP26 are a cause of juvenile myelomonocytic leukemia (JMML) [MIM:607785]. JMML is a pediatric myelodysplastic syndrome that constitutes approximay 30% of childhood cases of myelodysplastic syndrome (MDS) and 2% of leukemia. Chromosomal translocation t(5;11)(q31;q23) with MLL has been found in a JMML patient.
Similarity : Contains 1 PH domain. Contains 1 Rho-GAP domain. Contains 1 SH3 domain.
Database links : UniProtKB/Swiss-Prot: Q9UNA1.1
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