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Thrombin Receptor Antagonist trifluoroacetate salt

产品信息
  • 规格:0.5mg产品价格:1800.00
    规格:1mg产品价格:3000.00
    Catalog Number H-2514
    Synonyms T1
    Molecular Formula C₅₈H₉₁N₁₇O₂₀S₂
    Relative Molecular Mass 1410.60
    CAS Registry Number [207553-92-2]
    One Letter Code MSRPACPNDKYE
    Source Synthetic
    Storage Conditions -20 ± 5 °C
    Areas of Interest Cardiovascular System & Diseases|Hematology
    产品描述
    The peptide T1, MSRPACPNDKYE, is based on the sequence of the thrombin receptor domain that functions as a tethered ligand for the receptor itself. T1 has been selected from a phage peptide library as an inhibitor of thrombin triggered platelet aggregation, serotonin release and tyrosine phosphorylation. Its anti-aggregatory activity was about ten-fold higher than that of the previously reported peptide antagonists of the thrombin receptor.
    MSRPACPNDKYE has served as model peptide in protein modification and MS studies.
    论文引用
    • H.Y.Tang and D.W.Speicher, Anal. Biochem., 334, 48 (2004)
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