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原装进口 北京现货Recombinant Murine IL-13 价格 特价

产品信息
  • 原装进口 北京现货Recombinant Murine IL-13 价格 特价
          Catalog Number:
    210-13
    Synonyms:
    NC300 （Human） P600 （Murine）
    Description:
    IL-13 is an immunoregulatory cytokine produced primarily by activated Th2 cells, ａnd also by mast cells ａnd NK cells. Targeted deletion of IL-13 in mice resulted in impaired Th2 cell development ａnd indicated an important role for IL-13 in the expulsion of gastrointestinal parasites. IL-13 exerts anti-inflammatory effects on monocytes ａnd macrophages ａnd it inhibits the expression of inflammatory cytokines such as IL-1β, TNF-α, IL-6 ａnd IL-8. IL-13 has also been shown to enhance B cell proliferation ａnd to induce isotype switching resulting in increased production of IgE. Blocking of IL-13 activity inhibits the pathophysiology of asthma. Human ａnd murine IL-13 is cross-species reactive. Recombinant murine IL-13 is a 12.3 kDa protein consisting of 111 amino acid residues.
    AA Sequence:
    MPVPRSVSLP LTLKELIEEL SNITQDQTPL CNGSMVWSVD LAAGGFCVAL DSLTNISNCN AIYRTQRILH GLCNRKAPTT VSSLPDTKIE VAHFITKLLS YTKQLFRHGP F
    Source:
    E.coli
    Purity:
    Greater than 98% by SDS-PAGE gel ａnd HPLC analyses.
    Biological Activity:
    The ED50 as determined by the dose-dependent proliferation of TF-1 cells was < 4.0 ng/ml, corresponding to a specific activity of > 2.5 x 105 units/mg.
     
     
    Cross Reactivity:
    Human, Mouse
    Research Interests:
    AIDS / HIV Cancer
    Immune System Inflammation
    Stem Cells & Differentiation Allergy
     
     
    Country of Origin:
    USA
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