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Stemgent® Pax6 Antibody (Purified), Rabbit anti-Mouse/Human (100 μL)

产品信息
  • Product Overview

    Pax6 is a nuclear transcription factor essential for the development of the central nervous system, eyes, nose, and endocrine glands. The family of Pax genes encodes transcriptional regulators which are major controllers of development in both vertebrates and invertebrates. Mutations in this gene are known to cause ocular diseases such as aniridia and Peter's anomaly. Pax6 is required for the differentiation of pancreatic islet alpha cells and binds to glucagon, insulin, and somatostatin promoters. The Pax6 Antibody (Purified) was generated against the highly conserved peptide (QVPGSEPDMSQYWPRLQ) derived from the C-terminus of the mouse Pax6 protein. The protein has a predicted molecular weight of 47-50 kDa.

    Product Specifications
    Size

    100 μl

    Concentration

    0.5 mg/ml

    Clone

    Polyclonal

    Isotype

    Rabbit IgG

    Immunogen

    Peptide (QVPGSEPDMSQYWPRLQ) from the C-terminus of mouse Pax-6 protein

    Reactivity

    Mouse, Human

    Preparation

    This antibody was purified by affinity chromatography.

    Formulation

    Phosphate-buffered solution, pH 7.2, 0.1% sodium azide, and 0.2% BSA

    Storage and Stability

    Store at -20˚C protected from light. Stable for 6 months from date of receipt when stored as directed.

    Quality Control

    Tested by immunocytochemistry to ensure product quality.

    Recommended Usage

    The suggested use of this antibody is a 1:100 dilution for immunocytochemistry. For an application specific protocol, please reference Protocol: Immunocytochemistry online at www.stemgent.com/support/protocols. Additional reported applications include Western blot and immunohistochemistry.

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